MIEBO 1 mg/mg

Perfluorohexyloctane, the active ingredient in MIEBO, is a perfluorocarbon liquid (vitreous substitute) presented as a 1 mg/mg solution for ophthalmic use. It is used in retinal detachment repair, vitreoretinal surgery, and macular hole surgery. GNH USA supplies MIEBO as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals and clinics worldwide.

MIEBO is a prescription eye drop that forms a barrier over the eye to keep natural tears in place. It contains only perfluorohexyloctane, with no water and no preservatives. This semifluorinated alkane mixes with the lipid layer of the tear film to create a smooth, even coat that sharply reduces evaporation.

MIEBO is used in the treatment of conditions related to the retina and vitreous humor. It is particularly effective in the following conditions:

- Retinal detachment repair: Helps to flatten and re-attach the retina during surgery. - Vitreoretinal surgery: Provides a temporary intra-ocular tamponade to support surgical procedures. - Macular hole surgery: Assists in the closure and stabilization of macular holes.

MIEBO may cause certain side effects, although not everyone experiences them. Common side effects include:

Common Side Effects: - Blurred vision: Temporary visual disturbances may occur. - Eye redness: Mild irritation or redness of the eye. - Eye irritation: Mild discomfort or burning sensation.

Serious or Rare Side Effects: - Severe eye irritation: In rare cases, severe irritation may lead to treatment discontinuation. - Allergic reactions: Hypersensitivity reactions, though rare, can occur. - Vision changes: Persistent or severe changes in vision should be reported to a healthcare provider.

MIEBO should be used with caution and under the supervision of a healthcare provider. Important precautions include:

- Allergies: Do not use if allergic to perfluorohexyloctane. - Contact lenses: Remove contact lenses before use and wait at least 30 minutes before reinserting. - Pregnancy: Safety in pregnancy has not been established. - Pediatric use: Efficacy in children under 18 has not been established. - Administration: Use exactly as prescribed, typically one drop into each eye four times daily. - Storage: Store Miebo ophthalmic solution at 15ºC to 25ºC (59ºF to 77ºF). After opening, the ophthalmic solution can be used until the expiration date on the bottle.

MIEBO may interact with other medications or conditions. Major interactions to avoid include:

Major Interactions (Avoid): - None identified: No major interactions have been reported.

Moderate Interactions (Monitor Closely): - Other eye drops: Use of multiple eye drops may require spacing between applications. - Eye infections: Concurrent use with other ophthalmic treatments should be monitored. - Eye surgery: Coordination with surgical procedures is essential to avoid complications.