GNH USA

Europe — EMA

Midodrine Tillomed (Midodrine Hydrochloride)

GNH USA supplies Midodrine Tillomed (Midodrine Hydrochloride), an Alpha-1 adrenergic agonist for orthostatic hypotension. Request a quote for global supply.

Request sourcing

1
Pack/s

What is Midodrine Hydrochloride?

Midodrine Hydrochloride, the active ingredient in Midodrine Tillomed, is an Alpha-1 adrenergic agonist presented as an oral tablet for systemic use. It is used to raise blood pressure in patients with orthostatic hypotension, particularly adults who experience symptomatic drops upon standing. GNH USA supplies Midodrine Tillomed as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Midodrine Hydrochloride used for?

Midodrine Tillomed acts on the peripheral vascular system to treat low‑blood‑pressure conditions. - Orthostatic hypotension: increases standing blood pressure and reduces dizziness or fainting episodes in affected patients.

What are the side effects of Midodrine Hydrochloride?

Midodrine Tillomed may cause a range of adverse reactions.

Common Side Effects: - Piloerection: localized goose‑flesh skin reaction. - Pruritus: mild itching, often on the torso. - Urinary retention: difficulty emptying the bladder. - Supine hypertension: elevated blood pressure while lying down.

Serious or Rare Side Effects: - Severe hypertension: rapid, dangerous rise in blood pressure. - Bradycardia: unusually slow heart rate. - Allergic reaction: rash, swelling, or difficulty breathing.

What precautions apply to Midodrine Hydrochloride?

Before prescribing Midodrine Tillomed, clinicians should consider several safety measures. - Blood pressure monitoring: check supine and standing readings regularly. - Supine positioning: advise patients to avoid lying flat for prolonged periods. - Cardiovascular disease: use caution in patients with known heart conditions. - Renal impairment: dose adjustment may be needed in reduced kidney function. - Concomitant antihypertensives: assess risk of excessive blood pressure elevation. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

What does Midodrine Hydrochloride interact with?

Midodrine Tillomed can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis. - Other antihypertensive agents: additive blood‑pressure lowering effect. - Clonidine: may blunt the pressor response.

Moderate Interactions (Monitor Closely): - Diuretics: may amplify orthostatic changes. - Tricyclic antidepressants: potential for increased blood pressure. - Selective serotonin reuptake inhibitors (SSRIs): monitor for hypertension. - Non‑steroidal anti‑inflammatory drugs (NSAIDs): may affect renal handling of fluid.

Frequently asked questions

What is Midodrine Tillomed used for?+
Midodrine Tillomed is prescribed to treat orthostatic hypotension, a condition where blood pressure falls significantly upon standing, causing dizziness, light‑headedness, or fainting. By increasing vascular tone, the medication helps maintain adequate blood pressure when patients change posture.
How does Midodrine Hydrochloride work?+
Midodrine Hydrochloride is a pro‑drug that is converted in the body to desglymidodrine. The active metabolite binds to peripheral alpha‑1 adrenergic receptors, causing vasoconstriction of blood vessels, which raises systemic vascular resistance and elevates arterial blood pressure.
What is the usual dose of Midodrine Tillomed?+
The dosage of Midodrine Tillomed is individualized by the prescribing clinician based on the patient’s blood‑pressure response, severity of symptoms, and overall health status. The prescriber determines the appropriate amount, timing, and titration schedule.
Is Midodrine Tillomed safe during pregnancy or breastfeeding?+
Safety data for Midodrine Hydrochloride in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Healthcare providers should weigh potential benefits against possible risks before prescribing to pregnant or nursing individuals.
How do I order Midodrine Tillomed from GNH USA?+
To request Midodrine Tillomed, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Midodrine compare with other antihypotensive agents?+
Midodrine is unique as an oral alpha‑1 adrenergic agonist that directly increases vascular tone. Other antihypotensive options, such as fludrocortisone, act by expanding plasma volume. Choice of therapy depends on patient profile, comorbidities, and tolerance to side‑effects.
What are the storage requirements for Midodrine Tillomed?+
Midodrine Tillomed should be stored at room temperature, below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.
How is Midodrine Tillomed administered?+
Midodrine Tillomed is taken orally, usually with a full glass of water. It is commonly prescribed to be taken during the day, avoiding doses close to bedtime to reduce the risk of supine hypertension.
What are the most serious risks associated with Midodrine Tillomed?+
The most serious risks include severe hypertension, especially when lying down, and rare cases of bradycardia or allergic reactions. Patients should be educated to monitor blood pressure regularly and seek immediate medical attention if they experience chest pain, severe headache, or signs of an allergic response.
Who should not use Midodrine Tillomed?+
Midodrine is contraindicated in patients with known hypersensitivity to the drug, severe organic heart disease, uncontrolled hypertension, or those taking monoamine oxidase inhibitors. It should also be used with caution in individuals with renal impairment or a history of urinary retention.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Midodrine Hydrochloride
Route
Oral Use
Manufacturer
Tillomed Pharma Gmbh
Origin
EU

Related products