GNH USA

Europe — EMA

Microgynon 50

GNH USA supplies Microgynon 50 (Ethinylestradiol/Levonorgestrel), an oral contraceptive for preventing pregnancy and regulating menstrual cycles.

Ethinylestradiol, Levonorgestrel

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What is Ethinylestradiol, Levonorgestrel?

Ethinylestradiol, the active ingredient in Microgynon 50, is a combined oral contraceptive presented as a 50 µg/0.5 mg oral tablet for oral use. Together with levonorgestrel, it works to inhibit ovulation, thicken cervical mucus and alter the endometrium, providing reliable contraception and helping to regulate menstrual cycles in women of reproductive age.

GNH USA supplies Microgynon 50 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across markets.

What is Ethinylestradiol, Levonorgestrel used for?

Microgynon 50, a combined oral contraceptive, is used to manage reproductive health by influencing hormonal pathways.

- Prevention of pregnancy: provides reliable contraceptive protection for women of childbearing age. - Regulation of menstrual cycles: helps achieve more predictable cycle length and flow.

What are the side effects of Ethinylestradiol, Levonorgestrel?

Microgynon 50 may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: tension‑type or migraine‑like pain. - Breast tenderness: temporary swelling or soreness. - Spotting between periods: light vaginal bleeding.

Serious or Rare Side Effects: - Deep vein thrombosis: blood clot formation in deep veins. - Pulmonary embolism: clot traveling to the lungs. - Severe allergic reaction (anaphylaxis): rapid onset of hives, swelling, and breathing difficulty.

What precautions apply to Ethinylestradiol, Levonorgestrel?

Use of Microgynon 50 requires careful consideration of several safety factors.

- Contraindicated in pregnancy: product is Category X and must not be used by pregnant women. - Smoking and age over 35: increased risk of cardiovascular events. - History of thromboembolism: avoid use due to clotting risk. - Liver disease: use with caution as metabolism may be impaired. - Breastfeeding: consult a healthcare provider before use. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

What does Ethinylestradiol, Levonorgestrel interact with?

Microgynon 50 can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid): - Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): may reduce contraceptive effectiveness. - Rifampin and other antibiotics: may lower hormone levels. - Protease inhibitor antiretrovirals (e.g., ritonavir): may increase hormone concentrations and side‑effects.

Moderate Interactions (Monitor Closely): - Antifungal azoles (e.g., fluconazole): may raise hormone levels. - St. John’s wort: may decrease contraceptive efficacy. - Thiazide diuretics: may elevate risk of hypertension.

Frequently asked questions

What is Microgynon 50 used for?+
Microgynon 50 is a combined oral contraceptive containing ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy and to help regulate menstrual cycles in women of reproductive age.
How does ethinylestradiol work?+
Ethinylestradiol is a synthetic estrogen that binds to estrogen receptors, suppresses the hypothalamic‑pituitary‑gonadal axis, inhibits the luteinizing hormone surge, and stabilises the endometrium, all of which contribute to the contraceptive effect.
What is the usual dose of Microgynon 50?+
The dosage regimen is set by the prescribing healthcare professional. Typically, one tablet is taken daily at the same time for a 21‑day active phase followed by a 7‑day placebo interval, but exact instructions must follow the prescriber’s order.
Is Microgynon 50 safe in pregnancy or breastfeeding?+
Microgynon 50 is classified as pregnancy category X, meaning it must not be used during pregnancy. Use during breastfeeding should be discussed with a healthcare provider, as hormonal contraceptives are generally considered compatible but individual assessment is required.
How do I order Microgynon 50 from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.
How does Microgynon 50 compare with other combined oral contraceptives?+
Microgynon 50 contains a standard dose of 50 µg ethinylestradiol and 0.5 mg levonorgestrel, offering a balance of efficacy and tolerability. Compared with lower‑dose formulations, it may have a slightly higher risk of estrogen‑related side effects but provides reliable ovulation suppression.
How should Microgynon 50 be stored?+
Store at ambient temperature below 25 °C, in the original blister pack, protected from moisture and direct sunlight. Keep out of reach of children and do not use tablets that are discoloured or past the expiry date.
How is Microgynon 50 administered?+
The tablet is taken orally with water, preferably at the same time each day. No food restrictions are required, but swallowing the tablet whole is recommended. Follow the prescriber’s schedule for active and placebo days.
What are the most serious risks associated with Microgynon 50?+
Serious adverse events include venous thromboembolism, pulmonary embolism, myocardial infarction, stroke, and severe allergic reactions. Women with a history of clotting disorders, smoking over age 35, or certain cardiovascular conditions should avoid use.
Who should not use Microgynon 50?+
Contraindications include current pregnancy, known or suspected breast cancer, active liver disease, uncontrolled hypertension, history of thromboembolic events, and smokers over 35 years of age. Patients with these conditions should discuss alternative contraception with their healthcare provider.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Ethinylestradiol, Levonorgestrel
Route
Oral Use
Manufacturer
Bayer Sa Nv
Origin
EU

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