GNH USA

Europe — EMA

Microgynon 20 (Ethinylestradiol, Levonorgestrel)

GNH USA supplies Microgynon 20 (Ethinylestradiol / Levonorgestrel), a combined oral contraceptive for preventing pregnancy. Request a quote for global supply.

Ethinylestradiol, Levonorgestrel

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What is Ethinylestradiol, Levonorgestrel?

Ethinylestradiol, the active ingredient in Microgynon 20, is a combined oral contraceptive presented as a 20 µg ethinylestradiol / 100 µg levonorgestrel oral tablet for oral use. It prevents pregnancy by inhibiting ovulation and altering cervical mucus and endometrial lining in women of reproductive age.

GNH USA supplies Microgynon 20 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Ethinylestradiol, Levonorgestrel used for?

Microgynon 20, a combined oral contraceptive, acts on the hormonal regulation of the menstrual cycle to prevent pregnancy.

Contraception: provides reliable prevention of pregnancy for women of reproductive age. Menstrual cycle regulation: helps achieve more predictable bleeding patterns when taken continuously. Acne management: may improve moderate acne in women as a secondary therapeutic benefit.

What are the side effects of Ethinylestradiol, Levonorgestrel?

Adverse reactions may occur with any hormonal contraceptive.

Common Side Effects: - Nausea: mild stomach upset, often transient. - Headache: tension‑type or migraine‑like pain. - Breast tenderness: swelling or discomfort. - Irregular bleeding: spotting or breakthrough bleeding.

Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein clot formation. - Stroke: cerebrovascular accident, especially in high‑risk individuals. - Severe allergic reaction: rash, swelling, or anaphylaxis.

What precautions apply to Ethinylestradiol, Levonorgestrel?

Use of Microgynon 20 requires careful assessment of individual risk factors.

Contraindicated in pregnancy: product is Category X and must not be used by pregnant women. Avoid in history of thromboembolic disorders: increased risk of clot formation. Screen for hypertension: use with caution if blood pressure exceeds 140/90 mmHg. Do not use in smokers over age 35: heightened cardiovascular risk. Monitor liver function: contraindicated in severe hepatic impairment. Store at ambient temperature below 25°C: keep in the original pack, protect from moisture and light.

What does Ethinylestradiol, Levonorgestrel interact with?

Microgynon 20 may have clinically significant drug interactions.

Major Interactions (Avoid): - Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): reduce contraceptive effectiveness. - Rifampin and other rifamycins: lower hormone levels, increasing risk of unintended pregnancy. - Protease inhibitor antiretrovirals (e.g., ritonavir): may raise hormone concentrations, heightening side‑effect risk.

Moderate Interactions (Monitor Closely): - St. John’s wort: may diminish contraceptive efficacy. - Certain antibiotics (e.g., tetracycline): possible reduction in effectiveness. - SSRIs (e.g., fluoxetine): may increase plasma hormone levels.

Frequently asked questions

What is Microgynon 20 used for?+
Microgynon 20 is a combined oral contraceptive tablet that contains ethinylestradiol and levonorgestrel. It is prescribed to prevent pregnancy in women of reproductive age by inhibiting ovulation and creating cervical mucus conditions that are unfavorable for sperm. The product may also be used to help regulate menstrual cycles and, in some cases, to improve moderate acne.
How does ethinylestradiol and levonorgestrel work to prevent pregnancy?+
Ethinylestradiol provides estrogenic activity that stabilizes the uterine lining, while levonorgestrel, a synthetic progestogen, suppresses the mid‑cycle surge of luteinizing hormone, thereby preventing ovulation. Together they also thicken cervical mucus and alter the endometrium, creating an environment that hinders sperm penetration and implantation.
What is the usual dose of Microgynon 20?+
The dosing schedule for Microgynon 20 is determined by the prescribing healthcare professional. Typically, one tablet is taken orally each day for 21 consecutive days followed by a pill‑free interval, but the exact regimen, including any missed‑dose instructions, must be individualized by the prescriber.
Is Microgynon 20 safe to use during pregnancy or while breastfeeding?+
Microgynon 20 is classified as Pregnancy Category X, meaning it is contraindicated in pregnant women and must be discontinued if pregnancy occurs. While limited data exist for breastfeeding, most guidelines advise caution; the decision to use hormonal contraception while nursing should be made in consultation with a healthcare provider.
How do I order Microgynon 20 from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity of Microgynon 20. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Microgynon 20 compare with other combined oral contraceptives?+
Microgynon 20 contains 20 µg ethinylestradiol and 100 µg levonorgestrel, a low‑dose formulation that offers effective contraception with a reduced estrogen‑related risk profile. Compared with higher‑dose pills, it may have a lower incidence of estrogen‑related side effects, while maintaining comparable ovulation suppression. Choice of pill should consider individual risk factors, tolerability, and clinician preference.
How should Microgynon 20 be stored and handled?+
Microgynon 20 tablets should be stored at ambient temperature below 25 °C, in their original blister pack, protected from moisture and direct light. Do not refrigerate or freeze the tablets. Keep them out of reach of children and discard any tablets that appear damaged or discolored.
How is Microgynon 20 administered?+
Microgynon 20 is taken orally with water, preferably at the same time each day. A typical regimen involves one tablet daily for 21 days followed by a 7‑day pill‑free interval, during which withdrawal bleeding occurs. If a dose is missed, the patient should follow the specific missed‑dose instructions provided by the prescriber.
What are the most serious risks associated with Microgynon 20?+
The most serious adverse events include venous thromboembolism, stroke, myocardial infarction, and severe allergic reactions such as anaphylaxis. These risks are higher in women who smoke, are over 35 years old, have a history of clotting disorders, or have uncontrolled hypertension. Prompt medical attention is required if symptoms of clotting or severe reactions develop.
Who should not use Microgynon 20?+
Microgynon 20 is contraindicated in women who are pregnant or suspect they might be pregnant, have a history of thromboembolic disease, uncontrolled hypertension, severe liver disease, known or suspected breast cancer, or who are smokers over the age of 35. Individuals with known hypersensitivity to ethinylestradiol, levonorgestrel, or any tablet excipients should also avoid the product.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Ethinylestradiol, Levonorgestrel
Route
Oral Use
Manufacturer
Bayer B.V.
Origin
EU

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