Microgynon 20

Ethinylestradiol / Levonorgestrel, the active ingredient in Microgynon 20, is a combined oral contraceptive presented as a 20 µg/100 µg tablet for oral use. It prevents pregnancy in women of reproductive age by inhibiting ovulation and altering cervical mucus.

GNH USA supplies Microgynon 20 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing products that meet EU regulatory standards.

Microgynon 20, a combined oral contraceptive, is indicated for hormonal contraception to prevent pregnancy.

- Contraception: prevents pregnancy in women of reproductive age. - Menstrual cycle regulation: reduces irregular bleeding and helps establish a more predictable cycle. - Hormonal management: provides stable estrogen and progestogen levels for cycle control.

Microgynon 20 may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Breast tenderness: discomfort or swelling of the breasts. - Headache: occasional throbbing or tension‑type pain. - Breakthrough bleeding: spotting between periods. - Weight change: slight increase or decrease. - Mood changes: irritability or mood swings.

Serious or Rare Side Effects: - Venous thromboembolism: blood clots in deep veins. - Arterial thrombosis: clot formation in arteries, potentially leading to stroke or heart attack. - Hypertension: new‑onset or worsening high blood pressure. - Liver disorders: jaundice or hepatic dysfunction. - Severe allergic reaction: rash, swelling, or anaphylaxis.

Before prescribing Microgynon 20, clinicians should evaluate individual risk factors and provide appropriate counseling.

- Thromboembolic risk assessment: review personal and family history of clotting disorders. - Cardiovascular evaluation: check for hypertension, smoking >15 cigarettes/day, or uncontrolled diabetes. - Liver function review: avoid use in active liver disease. - Breast cancer screening: consider alternative methods in women with current or past breast cancer. - Missed dose guidance: advise backup contraception if tablets are omitted. - Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Microgynon 20 can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid): - Rifampicin and other strong enzyme inducers: markedly reduce contraceptive efficacy. - Certain antiretrovirals (e.g., efavirenz): may decrease hormone levels. - St. John’s wort: herbal inducer that can compromise protection.

Moderate Interactions (Monitor Closely): - Antifungals such as ketoconazole: may increase hormone concentrations. - Some antibiotics (e.g., tetracycline): possible slight reduction in effectiveness. - Selective serotonin reuptake inhibitors: may increase risk of mood‑related side effects. - Diuretics: may affect fluid balance and blood pressure. - Herbal supplements (e.g., ginseng): monitor for altered bleeding patterns.