Micrazym

Amylase, Lipase, Protease, the active ingredients in Micrazym, are an enzyme replacement therapy presented as an oral formulation for oral use. They aid patients with exocrine pancreatic insufficiency and related malabsorption disorders by supplying the digestive enzymes that the pancreas fails to produce sufficiently, catalyzing the breakdown of carbohydrates, fats and proteins to support nutrient absorption.

GNH USA supplies Micrazym as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Micrazym is used to support digestive function in conditions characterized by exocrine pancreatic insufficiency.

Exocrine pancreatic insufficiency: improves digestion of fats, proteins and carbohydrates by providing missing enzymes. Cystic fibrosis–related pancreatic insufficiency: enhances nutrient absorption in patients with cystic fibrosis. Chronic pancreatitis: reduces steatorrhea and malnutrition by supplementing pancreatic enzymes. Post‑pancreatic resection (e.g., after pancreatic cancer surgery): assists in maintaining adequate digestion after loss of pancreatic tissue.

Common Side Effects: - Abdominal discomfort or cramping. - Flatulence or gas. - Diarrhea or loose stools. - Nausea or mild vomiting. - Constipation. - Unpleasant taste or after‑taste.

Serious or Rare Side Effects: - Allergic reactions including rash, itching, or anaphylaxis. - Severe abdominal pain or pancreatitis exacerbation. - Persistent vomiting or dehydration. - Eosinophilia or other blood dyscrasias. - Intestinal obstruction. - Unexplained weight loss despite therapy.

Precautions should be observed when initiating Micrazym therapy.

Assess pancreatic function: confirm exocrine insufficiency before use. Monitor nutritional status: track weight, vitamin levels and stool consistency. Adjust dose in renal or hepatic impairment: consider reduced dosing if organ function is compromised. Avoid use in known hypersensitivity: discontinue if allergic signs appear. Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Micrazym may interact with other agents that affect gastric pH or fat digestion.

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: may reduce enzyme activity. - Proton pump inhibitors: altered gastric acidity can affect enzyme efficacy. - Broad‑spectrum antibiotics: disruption of gut flora may modify digestion.

Moderate Interactions (Monitor Closely): - Orlistat: concurrent use may interfere with fat digestion. - High‑fat meals: may require dose adjustment for optimal effect. - Fat‑soluble vitamin supplements: monitor levels as absorption may change.