GNH USA

Europe — EMA

Miclodin

GNH USA supplies Miclodin (Clotrimazole), an azole antifungal for vaginal candidiasis. Request a quote for worldwide hospital and pharmacy reliable supply.

Clotrimazole

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Pack/s

What is Clotrimazole?

Clotrimazole, the active ingredient in Miclodin, is an azole antifungal presented as a vaginal formulation for local use. It treats vaginal candidiasis, a common yeast infection, in adult women. The medication works by targeting fungal cell membranes, helping to relieve symptoms such as itching, discharge, and irritation.

GNH USA supplies Miclodin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, ensuring product integrity throughout the supply chain.

What is Clotrimazole used for?

Miclodin, an azole antifungal, acts on Candida species that cause vaginal infections. - Vaginal candidiasis: eliminates the fungal infection and relieves associated symptoms. - Recurrent vaginal candidiasis: used as prescribed to reduce the frequency of future episodes. - Yeast infection of the vagina: helps restore normal vaginal flora by inhibiting fungal growth.

What are the side effects of Clotrimazole?

Miclodin may cause local adverse reactions when applied vaginally.

Common Side Effects: - Irritation or burning sensation at the application site. - Mild itching or redness. - Vaginal discharge that may be watery or whitish. - Dryness of the vaginal mucosa. - Mild allergic skin reaction (rash). - Unpleasant odor.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling, hives, or difficulty breathing. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Significant vaginal ulceration or ulcerative lesions. - Persistent or worsening irritation. - Hepatotoxicity (very rare with topical use). - Systemic fungal infection if extensive mucosal damage occurs.

What precautions apply to Clotrimazole?

Before using Miclodin, consider the following safety measures. - Pregnancy: consult a healthcare provider before use, as safety data are limited. - Breastfeeding: discuss potential risks with a physician. - Allergy: avoid if you have known hypersensitivity to clotrimazole or other azole antifungals. - Concurrent vaginal products: do not use other intravaginal medications simultaneously without medical advice. - Duration of therapy: follow the prescribed treatment length and avoid prolonged use without supervision. - Store at room temperature: keep in the original packaging, protect from moisture and heat.

What does Clotrimazole interact with?

Miclodin may interact with other medicines; monitor as indicated.

Major Interactions (Avoid): - Systemic azole antifungals (e.g., fluconazole): concurrent use can increase systemic exposure and toxicity. - Oral hormonal contraceptives: topical azoles may reduce contraceptive effectiveness.

Moderate Interactions (Monitor Closely): - Topical steroids: may mask local irritation or infection signs. - Other intravaginal medications (e.g., spermicides): monitor for reduced efficacy or increased irritation. - Antifungal resistance: avoid overuse to prevent development of resistant Candida strains.

Frequently asked questions

What is Miclodin used for?+
Miclodin contains clotrimazole and is used to treat vaginal candidiasis, a common yeast infection in women. It works by eliminating the Candida fungus that causes symptoms such as itching, discharge, and irritation.
How does clotrimazole work in Miclodin?+
Clotrimazole inhibits the fungal enzyme lanosterol 14α‑demethylase, which is essential for ergosterol synthesis. Without ergosterol, the fungal cell membrane becomes unstable, leading to cell death and clearance of the infection.
What is the usual dose of Miclodin?+
The prescribed dose of Miclodin is determined by the treating clinician based on the severity of the infection and patient-specific factors. Patients should follow the healthcare professional’s instructions and not alter the regimen on their own.
Is Miclodin safe during pregnancy or breastfeeding?+
Safety data for clotrimazole in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Miclodin.
How do I order Miclodin from GNH USA?+
To order Miclodin, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Miclodin compare with other antifungal treatments?+
Miclodin (clotrimazole) belongs to the azole class and is comparable to other topical azoles such as miconazole. It offers a similar spectrum of activity against Candida species, but formulation, dosing frequency and local tolerability may differ, influencing clinician choice.
What are the storage and handling requirements for Miclodin?+
Miclodin should be stored at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and excessive heat to maintain product stability and efficacy.
How is Miclodin administered?+
Miclodin is applied intravaginally. The patient inserts the dosage form (tablet, cream, or suppository) into the vagina as directed by the prescriber, usually before bedtime, and avoids intercourse or douching for the recommended period.
What are the most serious risks associated with Miclodin?+
Serious risks, though rare, include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, and significant vaginal ulceration. Patients should seek immediate medical attention if they experience swelling, rash, blistering, or worsening irritation.
Who should not use Miclodin?+
Miclodin should not be used by individuals with a known hypersensitivity to clotrimazole or any azole antifungal. It is also contraindicated in patients with active severe vaginal ulceration or those advised against intravaginal products by their clinician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Clotrimazole
Route
Vaginal Use
Manufacturer
Zaklady Farmaceutyczne Polpharma S.A.
Origin
EU

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