Micasal

Tyrothricin, the active ingredient in Micasal, is a polypeptide antibiotic presented as a topical preparation for external use. It treats superficial bacterial skin infections in adults and children.

GNH USA supplies Micasal as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Tyrothricin is applied to the skin to address bacterial conditions affecting the epidermis and superficial tissues.

- Minor skin infections: reduces bacterial load and supports healing of localized infections. - Superficial wound infections: prevents colonisation of bacteria in small cuts or abrasions. - Burns and abrasions: provides antibacterial protection to damaged skin surfaces.

Topical application of Tyrothricin may cause local reactions in some users.

Common Side Effects: - Skin irritation: mild redness or burning at the application site. - Itching: transient pruritus around the treated area. - Dryness: temporary loss of moisture on the skin. - Contact dermatitis: mild allergic skin response. - Stinging sensation: brief discomfort upon first use. - Erythema: localized redness.

Serious or Rare Side Effects: - Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention. - Stevens‑Johnson syndrome: rare but serious mucocutaneous disorder. - Bullous dermatitis: formation of blisters on the skin. - Systemic toxicity: extremely rare absorption leading to systemic effects. - Necrotizing fasciitis: very rare, secondary infection. - Persistent ulceration: prolonged skin breakdown at the site.

When using Tyrothricin, consider the following safety measures.

- Allergy assessment: avoid if known hypersensitivity to tyrothricin or related polypeptide antibiotics. - Application area: limit use to intact skin; do not apply to mucous membranes or open wounds unless directed. - Age restrictions: not recommended for infants under two months without medical supervision. - Concurrent skin conditions: use with caution on eczema, psoriasis, or other compromised skin. - Pregnancy and lactation: consult a healthcare professional before use. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Tyrothricin may interact with other topical agents, affecting efficacy or irritation risk.

Major Interactions (Avoid): - Other topical antibiotics: increased risk of local irritation. - Topical corticosteroids: may reduce antibacterial effectiveness. - Occlusive dressings: can enhance absorption leading to irritation.

Moderate Interactions (Monitor Closely): - Antiseptics such as chlorhexidine: possible chemical incompatibility. - Alcohol‑based moisturizers: may increase skin irritation. - Phototoxic agents: heightened risk of photosensitivity when exposed to sunlight.