Mibetin

Betamethasone dipropionate and Gentamicin sulfate, the active ingredients in Mibetin, are a corticosteroid/antibiotic combination presented as a topical formulation for skin application. They are used to reduce inflammation and treat bacterial infection in inflammatory skin conditions such as eczema, dermatitis, and infected psoriasis in adult and pediatric patients.

GNH USA supplies Mibetin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows stringent quality standards and provides regulatory documentation for global distribution, including batch release certificates and stability data.

Mibetin combines a corticosteroid and an antibiotic to treat inflammatory and infected skin conditions.

Eczema: reduces inflammation and controls secondary bacterial infection. Contact dermatitis: alleviates redness, swelling and prevents bacterial colonisation. Infected psoriasis: diminishes plaque inflammation while treating accompanying bacterial infection.

Topical application of Mibetin may be associated with local adverse reactions.

Common Side Effects: - Skin irritation: mild redness or burning at the application site. - Pruritus: itching sensation. - Dryness: localized skin dryness. - Folliculitis: small pustules around hair follicles.

Serious or Rare Side Effects: - Hypersensitivity: severe rash, swelling or anaphylaxis. - Skin atrophy: thinning of the epidermis with prolonged use. - Secondary infection: overgrowth of non‑susceptible organisms. - Systemic corticosteroid effects: adrenal suppression with extensive application.

Before using Mibetin, consider the following precautions to minimise risks.

Assess infection type: confirm bacterial involvement to justify Gentamicin use. Limit duration: use for the shortest effective period to reduce steroid‑related skin changes. Avoid occlusion: do not cover treated area with airtight dressings unless directed. Monitor for systemic absorption: especially in extensive or broken skin, watch for adrenal effects. Pregnancy and lactation: discuss potential risks with a healthcare professional. Store at ambient temperature: keep in the original container, protect from moisture and light.

Mibetin may interact with other medications applied to the skin or systemic agents.

Major Interactions (Avoid): - Concurrent use of other potent topical steroids: may increase risk of skin atrophy. - Systemic corticosteroids: additive systemic glucocorticoid effects.

Moderate Interactions (Monitor Closely): - Topical calcineurin inhibitors: monitor for combined immunosuppression. - Antibiotics with ototoxic potential: caution if large areas applied near ears. - Antifungal agents: may reduce efficacy of Gentamicin against mixed infections.