GNH USA

Europe — EMA

Mgd 400 Direct Ee

GNH USA supplies Mgd 400 Direct Ee (Magnesium), a mineral supplement for magnesium deficiency and hypomagnesemia.

Magnesium Oxide, Heavy, Magnesium Citrate Dibasic

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What is Magnesium Oxide, Heavy, Magnesium Citrate Dibasic?

Magnesium oxide, the active ingredient in Mgd 400 Direct Ee, is a mineral supplement presented as an oral tablet for oral use. It is employed to treat magnesium deficiency and related electrolyte disturbances in adults and supports normal neuromuscular and cardiovascular function.

GNH USA supplies Mgd 400 Direct Ee as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide with consistent quality and regulatory compliance.

What is Magnesium Oxide, Heavy, Magnesium Citrate Dibasic used for?

Mgd 400 Direct Ee is used to address conditions associated with low magnesium levels.

- Magnesium deficiency: restores normal magnesium stores and supports enzymatic processes. - Hypomagnesemia: raises serum magnesium concentration to therapeutic range. - Post‑operative care: helps maintain electrolyte balance during recovery. - Pregnancy‑related magnesium loss: supplements maternal magnesium needs.

What are the side effects of Magnesium Oxide, Heavy, Magnesium Citrate Dibasic?

Adverse reactions may occur with magnesium supplementation, ranging from mild gastrointestinal symptoms to rare systemic events.

Common Side Effects: - Diarrhea - Abdominal cramping - Nausea - Flatulence - Constipation - Metallic taste

Serious or Rare Side Effects: - Hypermagnesemia - Severe allergic reaction (anaphylaxis) - Cardiac arrhythmia - Muscle weakness - Low blood pressure - Respiratory depression

What precautions apply to Magnesium Oxide, Heavy, Magnesium Citrate Dibasic?

Use of magnesium supplements requires attention to certain health conditions and handling practices.

- Renal impairment: monitor serum magnesium and adjust dose. - Cardiac disease: use caution due to potential effects on conduction. - Concurrent laxative use: may increase magnesium absorption. - Pregnancy: safety not established; consult a healthcare provider. - Drug interactions: review concomitant medications. - Store at room temperature: keep in original container, protect from moisture and heat.

What does Magnesium Oxide, Heavy, Magnesium Citrate Dibasic interact with?

Magnesium can interact with several medications, affecting absorption or physiological effects.

Major Interactions (Avoid): - Antacids containing aluminum or calcium: may reduce magnesium absorption. - Tetracycline or fluoroquinolone antibiotics: chelation reduces efficacy. - Bisphosphonates: concurrent use impairs absorption.

Moderate Interactions (Monitor Closely): - Loop or thiazide diuretics: may increase risk of hypermagnesemia. - ACE inhibitors or ARBs: monitor blood pressure and electrolytes. - Cardiac glycosides: magnesium levels can affect toxicity.

Frequently asked questions

What is Mgd 400 Direct Ee used for?+
Mgd 400 Direct Ee is an oral magnesium supplement used to correct magnesium deficiency, treat hypomagnesemia, and support normal electrolyte balance in adults.
How does magnesium oxide work in the body?+
Magnesium oxide releases magnesium ions after dissolution, which act as cofactors for many enzymatic reactions, helping regulate neuromuscular activity, cardiac function, and energy metabolism.
What is the usual dose of Mgd 400 Direct Ee?+
The appropriate dose is determined by the prescribing healthcare professional based on the individual’s clinical condition, laboratory values, and overall health status.
Is Mgd 400 Direct Ee safe during pregnancy or breastfeeding?+
Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using the product.
How do I order Mgd 400 Direct Ee from GNH USA?+
Submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Mgd 400 Direct Ee compare with other magnesium supplements?+
Mgd 400 Direct Ee combines magnesium oxide and magnesium citrate dibasic, offering both a high elemental magnesium content and good bioavailability, whereas some alternatives may contain only one magnesium salt, affecting absorption rates and gastrointestinal tolerance.
What are the storage requirements for Mgd 400 Direct Ee?+
Store at room temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, direct sunlight, and excessive heat to maintain potency.
How is Mgd 400 Direct Ee administered?+
The product is taken orally, usually with water. It can be swallowed with or without food, following the dosage instructions provided by the prescriber.
What are the most serious risks associated with Mgd 400 Direct Ee?+
The most serious risks include hypermagnesemia, which can cause cardiac arrhythmias, severe hypotension, respiratory depression, and, in rare cases, life‑threatening allergic reactions.
Who should not use Mgd 400 Direct Ee?+
Individuals with severe renal impairment, known hypersensitivity to magnesium salts, or those on medications that may cause dangerous electrolyte shifts should avoid using this supplement unless directed by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Magnesium Oxide, Heavy, Magnesium Citrate Dibasic
Route
Oral Use
Manufacturer
Protina Pharmazeutische Gesellschaft Mbh
Origin
EU

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