GNH USA

Europe — EMA

Mexylor (Lormetazepam)

GNH USA supplies Mexylor (Lormetazepam), a benzodiazepine hypnotic for short‑term treatment of insomnia. Request a quote for global supply to hospitals.

Lormetazepam

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1
Pack/s

What is Lormetazepam?

Lormetazepam, the active ingredient in Mexylor, is a benzodiazepine presented as an oral formulation for oral use. It is used for short‑term treatment of insomnia in adults. GNH USA supplies Mexylor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Lormetazepam used for?

Lormetazepam acts on the central nervous system to promote sleep in patients with insomnia.

Insomnia: facilitates sleep initiation and maintenance during short‑term therapy. Sleep onset insomnia: reduces the time required to fall asleep. Sleep maintenance insomnia: decreases the number of nocturnal awakenings.

What are the side effects of Lormetazepam?

Lormetazepam may cause a range of adverse reactions, some of which are frequent while others are rare but serious.

Common Side Effects: - Drowsiness - Fatigue - Dizziness - Ataxia - Memory impairment - Headache

Serious or Rare Side Effects: - Respiratory depression - Dependence or withdrawal syndrome - Paradoxical reactions such as agitation - Severe allergic reactions (e.g., rash, angioedema) - Depression or suicidal ideation - Hepatic dysfunction

What precautions apply to Lormetazepam?

When prescribing Lormetazepam, clinicians should consider several safety measures.

Assess treatment duration: limit use to short‑term periods to avoid dependence. Avoid in severe respiratory insufficiency: risk of respiratory depression. Exercise caution in the elderly: increased fall and fracture risk. Do not combine with alcohol or other CNS depressants: additive sedation. Monitor for signs of dependence or abuse. Store at ambient temperature: keep in the original pack, protect from moisture.

What does Lormetazepam interact with?

Lormetazepam can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Alcohol: additive central nervous system depression. - Opioids: heightened risk of respiratory depression. - Other benzodiazepines: cumulative sedative effect.

Moderate Interactions (Monitor Closely): - SSRIs or other antidepressants: may increase sedation. - Antihistamines: additive drowsiness. - CYP3A4 inhibitors (e.g., ketoconazole): may raise plasma concentrations of lormetazepam.

Frequently asked questions

What is Mexylor used for?+
Mexylor contains lormetazepam and is indicated for the short‑term treatment of insomnia in adult patients. It helps initiate and maintain sleep when used for a limited period, typically a few nights to a few weeks, under medical supervision.
How does lormetazepam work?+
Lormetazepam enhances the activity of the neurotransmitter GABA at the GABA‑A receptor. By acting as a positive allosteric modulator, it increases chloride ion flow into neurons, producing a calming effect that reduces brain activity and facilitates sleep.
What is the usual dose of Mexylor?+
The specific dose of Mexylor is determined by the prescribing clinician based on the patient’s age, health status, and severity of insomnia. Physicians typically start with the lowest effective dose and adjust as needed, following local prescribing guidelines.
Is Mexylor safe during pregnancy or breastfeeding?+
Safety data for lormetazepam in pregnancy and lactation are limited. Because benzodiazepines may cross the placenta and appear in breast milk, the drug is generally avoided unless the potential benefit outweighs the risk. Consultation with a healthcare professional is essential.
How do I order Mexylor from GNH USA?+
To order Mexylor, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Mexylor compare with other insomnia medications?+
Mexylor belongs to the benzodiazepine class, offering rapid onset of sleep but a higher potential for dependence compared with non‑benzodiazepine hypnotics such as zolpidem. It is generally reserved for short‑term use, whereas newer agents may be preferred for longer‑term management.
How should Mexylor be stored and handled?+
Store Mexylor at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.
How is Mexylor administered?+
Mexylor is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed. It is usually taken shortly before bedtime, and patients should avoid taking it with or after a heavy meal that might delay absorption.
What are the most serious risks associated with Mexylor?+
The most serious risks include the development of physical dependence, withdrawal symptoms upon abrupt discontinuation, respiratory depression—especially when combined with other depressants—and rare but severe allergic reactions. Monitoring for these effects is essential during therapy.
Who should not use Mexylor?+
Mexylor should be avoided in patients with known hypersensitivity to lormetazepam or other benzodiazepines, those with severe respiratory insufficiency, acute narrow‑angle glaucoma, or a history of substance dependence. Caution is also advised for the elderly and individuals with hepatic impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Lormetazepam
Route
Oral Use
Manufacturer
Epifarma S.R.L.
Origin
EU

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