Mexilon

Meloxicam, the active ingredient in Mexilon, is a nonsteroidal anti-inflammatory drug presented as an injectable solution for intramuscular use. It treats pain and inflammation associated with osteoarthritis, rheumatoid arthritis and other musculoskeletal conditions in adults.

GNH USA supplies Mexilon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Meloxicam is an NSAID used to manage inflammatory and painful conditions affecting the musculoskeletal system.

- Osteoarthritis: reduces joint pain and improves functional mobility. - Rheumatoid arthritis: decreases synovial inflammation and limits disease‑related damage. - Acute pain: provides rapid analgesia for postoperative or injury‑related pain.

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects: - Gastrointestinal upset (nausea, dyspepsia) - Headache - Dizziness - Injection‑site pain or erythema - Mild skin rash - Elevated liver enzymes

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding - Severe cutaneous reactions (e.g., Stevens‑Johnson syndrome) - Acute renal impairment or failure - Cardiovascular events such as myocardial infarction - Anaphylactic or anaphylactoid reactions - Hepatic failure or severe hepatitis

When prescribing meloxicam, clinicians should consider several safety measures.

- Renal function assessment: evaluate baseline kidney status before initiation. - Hepatic monitoring: check liver enzymes periodically during treatment. - Dose minimisation: use the lowest effective dose for the shortest duration needed. - Hypersensitivity avoidance: discontinue if signs of allergic reaction appear. - Concomitant anticoagulant caution: monitor bleeding risk when combined with warfarin or similar agents. - Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake the vial.

Meloxicam can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Other NSAIDs or aspirin: heightened gastrointestinal toxicity. - ACE inhibitors or ARBs: may reduce renal function, especially in dehydrated patients.

Moderate Interactions (Monitor Closely): - Lithium: meloxicam may raise lithium serum levels, requiring dose adjustment. - Methotrexate: potential for enhanced methotrexate toxicity; monitor blood counts and liver function.