Mexalen

Paracetamol, the active ingredient in Mexalen, is an analgesic presented as an oral tablet for oral use. It reduces fever and relieves mild to moderate pain in adults and children. GNH USA supplies Mexalen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Paracetamol acts as an antipyretic and analgesic, addressing common pain and fever pathways.

Fever: lowers elevated body temperature to normal levels. Headache: alleviates tension‑type and mild migraine pain. Musculoskeletal pain: reduces discomfort from strains, sprains and minor injuries. Dental pain: eases pain associated with toothaches and dental procedures. Menstrual discomfort: helps relieve mild dysmenorrhea.

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Nausea or stomach upset - Mild abdominal discomfort - Transient headache - Dizziness or light‑headedness - Skin rash or mild itching - Sweating or flushing

Serious or Rare Side Effects: - Severe skin reactions such as Stevens‑Johnson syndrome - Hepatotoxicity, especially with overdose or chronic use - Blood disorders including thrombocytopenia - Anaphylactic or severe allergic reactions - Acute renal failure in susceptible individuals - Hypersensitivity with angioedema

Paracetamol should be used with awareness of safety considerations. - Dose limitation: do not exceed the maximum daily amount recommended by a healthcare professional. - Alcohol avoidance: limit alcohol intake to reduce liver stress. - Liver monitoring: assess hepatic function in patients with existing liver disease. - Hypersensitivity: discontinue use if rash, swelling or breathing difficulty develop. - Pregnancy and breastfeeding: consult a physician before use. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Paracetamol may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Warfarin: increased risk of bleeding. - Carbamazepine: reduced analgesic effect. - Isoniazid: heightened potential for liver toxicity. - Alcohol: synergistic hepatotoxicity.

Moderate Interactions (Monitor Closely): - Oral contraceptives: possible reduction in contraceptive efficacy. - Phenytoin: may lower paracetamol plasma levels. - HIV protease inhibitors: altered metabolism increasing exposure. - Fluconazole: may increase paracetamol concentrations.