Metuxtan Sr

Metformin Hydrochloride, the active ingredient in Metuxtan Sr, is a biguanide presented as an oral tablet for oral use. It is employed to improve glycemic control in adults with type 2 diabetes mellitus by decreasing hepatic glucose production and enhancing peripheral insulin sensitivity, thereby helping to lower blood sugar levels.

GNH USA supplies Metuxtan Sr as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global logistics for regulated medicines.

Metuxtan Sr (metformin hydrochloride) is used in the management of disorders related to impaired glucose regulation.

Type 2 diabetes mellitus: improves glycemic control by lowering fasting and post‑prandial blood glucose levels.

Metuxtan Sr may be associated with a range of adverse reactions, varying from mild to serious.

Common Side Effects: - Nausea and abdominal discomfort - Diarrhea - Metallic taste in the mouth

Serious or Rare Side Effects: - Lactic acidosis (potentially fatal) - Severe skin reactions such as Stevens‑Johnson syndrome - Hepatic failure

Before prescribing Metuxtan Sr, clinicians should consider several safety measures. - Renal function: assess eGFR before initiation and monitor periodically - Hepatic function: avoid use in patients with severe liver disease - Contraindicated in patients with eGFR <30 mL/min/1.73 m² - Use with caution in elderly patients due to increased risk of lactic acidosis - Avoid excessive alcohol consumption - Store at ambient temperature: keep in the original pack, protect from moisture

Metuxtan Sr can interact with other medicines, requiring careful management.

Major Interactions (Avoid): - Iodinated contrast agents (risk of acute renal failure) - Cimetidine (increases metformin plasma concentrations) - Certain antiretrovirals, such as protease inhibitors (raise risk of lactic acidosis)

Moderate Interactions (Monitor Closely): - Beta‑blockers (may mask hypoglycemia symptoms) - ACE inhibitors or ARBs (affect renal function) - NSAIDs (reduce renal clearance of metformin) - Alcohol (enhances risk of lactic acidosis)