GNH USA

Europe — EMA

Metrosa

GNH USA supplies Metrosa (Metronidazole), a nitroimidazole antibiotic for rosacea, acne vulgaris and bacterial skin infections. Request a quote for supply.

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metrosa, is a nitroimidazole antibiotic presented as a topical for topical use. It treats bacterial skin infections, rosacea and acne vulgaris in adults.

GNH USA supplies Metrosa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metronidazole used for?

Metrosa is a nitroimidazole antibiotic used to manage skin conditions caused by susceptible anaerobic bacteria and inflammation.

Rosacea: reduces inflammatory lesions and erythema associated with the condition. Acne vulgaris: decreases papules, pustules and redness. Bacterial skin infections: eradicates susceptible organisms and promotes lesion healing.

What are the side effects of Metronidazole?

Metrosa may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation or burning sensation at the application site. - Itching or pruritus. - Dryness or peeling of the treated skin. - Redness or mild erythema.

Serious or Rare Side Effects: - Allergic reactions such as urticaria or angioedema. - Severe skin rash or Stevens‑Johnson syndrome. - Photosensitivity leading to exaggerated sunburn. - Contact dermatitis. - Systemic toxicity (rare) presenting as neurotoxicity or hepatic dysfunction.

What precautions apply to Metronidazole?

Before using Metrosa, consider the following safety measures.

Pregnancy: Category B – use only if clearly needed after risk‑benefit assessment. Breastfeeding: Small amounts may be excreted in milk; evaluate necessity. Skin integrity: Avoid application on extensive open wounds or mucous membranes. Alcohol consumption: Limit intake to reduce risk of disulfiram‑like reaction. Allergy: Discontinue if signs of hypersensitivity develop. Store at ambient temperature: keep below 25 °C, in original container, protected from moisture and direct light.

What does Metronidazole interact with?

Metrosa can interact with several systemic medications; monitor patients accordingly.

Major Interactions (Avoid): - Alcohol: may cause a disulfiram‑like reaction with flushing and nausea. - Warfarin: can potentiate anticoagulant effect, increasing bleeding risk. - Lithium: may raise lithium levels, risking toxicity. - Cimetidine: may increase metronidazole plasma concentrations.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce hormonal efficacy, consider alternative contraception. - Phenobarbital: may lower metronidazole levels, potentially reducing effectiveness.

Frequently asked questions

What conditions is Metrosa used to treat?+
Metrosa is a topical formulation of metronidazole indicated for the treatment of rosacea, acne vulgaris, and bacterial skin infections caused by susceptible anaerobic organisms. It helps reduce inflammation, lesions, and bacterial load on the skin.
How does metronidazole work in Metrosa?+
Metronidazole is reduced inside anaerobic microorganisms to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to bacterial cell death. This mechanism reduces the microbial burden and associated inflammation in the skin.
What is the usual dose of Metrosa?+
The dosage and frequency of Metrosa are determined by the prescribing clinician based on the specific indication, severity of the condition, and patient factors. Patients should follow the prescriber’s instructions and the product label.
Is Metrosa safe to use during pregnancy or breastfeeding?+
Metrosa is classified as Pregnancy Category B, indicating no evidence of risk in animal studies but a lack of well‑controlled studies in humans. It should be used during pregnancy only if clearly needed. Small amounts may be excreted in breast milk; breastfeeding decisions should consider the benefit‑risk balance.
How do I order Metrosa from GNH USA?+
To order Metrosa, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metrosa compare with other topical acne treatments?+
Metrosa (topical metronidazole) offers anti‑inflammatory and antibacterial effects, particularly against anaerobic bacteria. Compared with agents like benzoyl peroxide or topical antibiotics such as clindamycin, metronidazole may have a lower risk of bacterial resistance and is especially useful for rosacea‑associated acne.
What are the recommended storage conditions for Metrosa?+
Metrosa should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed when not in use.
How is Metrosa applied?+
Metrosa is applied topically to the affected skin area, typically once or twice daily as directed by the prescriber. The skin should be clean and dry before application, and the medication should be spread in a thin layer and gently rubbed in.
What are the most serious risks associated with Metrosa?+
Serious risks, though rare, include severe allergic reactions such as urticaria, angioedema, Stevens‑Johnson syndrome, and photosensitivity. Systemic toxicity can occur if large amounts are absorbed, presenting as neurotoxicity or hepatic dysfunction. Patients should seek immediate medical attention if serious symptoms develop.
Who should not use Metrosa?+
Metrosa should not be used by individuals with known hypersensitivity to metronidazole or other nitroimidazole compounds. It is also contraindicated on extensive open wounds, mucous membranes, or in patients where the risk of severe allergic reactions outweighs potential benefits.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Cutaneous Use
Manufacturer
Dr. August Wolff Gmbh & Co. Kg Arzneimittel
Origin
EU

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