Metronidazole Sg-Pharm

Metronidazole, the active ingredient in Metronidazole Sg-Pharm, is a nitroimidazole antibiotic presented as an oral tablet for systemic use. It treats a range of anaerobic bacterial and protozoal infections in adults and children as prescribed by a healthcare professional.

GNH USA supplies Metronidazole Sg-Pharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable global distribution.

Metronidazole is used to treat infections caused by anaerobic bacteria and certain protozoa. It is effective in several clinical settings: - Bacterial vaginosis: eradicates the anaerobic bacteria responsible for the condition, relieving discharge and odor. - Trichomoniasis: eliminates Trichomonas vaginalis, curing infection and preventing transmission. - Amoebiasis: destroys Entamoeba histolytica trophozoites, treating intestinal and extra‑intestinal disease. - Giardiasis: clears Giardia lamblia from the gastrointestinal tract, resolving diarrhea and malabsorption. - Clostridioides difficile infection: suppresses toxin‑producing C. difficile, aiding recovery from colitis. - Anaerobic bacterial infections: targets a broad spectrum of anaerobes in intra‑abdominal, pelvic and skin‑soft‑tissue infections.

Metronidazole may cause adverse reactions that vary in frequency and severity.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Diarrhea: loose stools that may be watery. - Headache: mild to moderate head discomfort.

Serious or Rare Side Effects: - Seizures: rare neurologic events requiring immediate care. - Peripheral neuropathy: tingling or numbness in extremities. - Severe allergic reaction: hives, swelling, or anaphylaxis.

Before prescribing Metronidazole, consider the following safety measures: - Pregnancy: Category B – use only if the potential benefit justifies the potential risk to the fetus. - Liver function: monitor hepatic enzymes in patients with liver disease. - Alcohol consumption: avoid alcohol to prevent a disulfiram‑like reaction. - Renal impairment: adjust therapy in severe kidney dysfunction. - Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Metronidazole can interact with several medicines; awareness of interaction severity helps guide monitoring.

Major Interactions (Avoid): - Alcohol: may cause severe flushing, tachycardia, and hypotension. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk. - Lithium: may raise lithium levels, leading to toxicity.

Moderate Interactions (Monitor Closely): - Phenytoin: reduces phenytoin concentrations, possibly decreasing seizure control. - Cimetidine: can increase metronidazole plasma levels, enhancing side effects. - Oral contraceptives: may reduce hormonal efficacy, requiring additional contraceptive measures.