GNH USA

Europe — EMA

Metronidazole Braun

GNH USA supplies Metronidazole Braun (Metronidazole), a nitroimidazole antibiotic for anaerobic bacterial infections, bacterial vaginosis, and related

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazole Braun, is a nitroimidazole presented as an injection for intravenous use. It treats anaerobic bacterial infections and related conditions in both adult and pediatric patients as prescribed by a healthcare professional, including bacterial vaginosis, trichomoniasis, amebic liver abscess, and Clostridioides difficile infection.

GNH USA supplies Metronidazole Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, tertiary care centers, and specialty clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for global distribution.

What is Metronidazole used for?

Metronidazole Braun is used to treat infections caused by anaerobic bacteria and certain protozoa. - Anaerobic bacterial infections: effective against a broad range of anaerobic organisms, reducing infection severity. - Bacterial vaginosis: restores normal vaginal flora by eliminating pathogenic anaerobes. - Trichomoniasis: eradicates the protozoan parasite Trichomonas vaginalis. - Amebic liver abscess: targets Entamoeba histolytica to resolve hepatic lesions. - Clostridioides difficile infection: suppresses toxin‑producing C. difficile strains in the colon.

What are the side effects of Metronidazole?

Common side effects are typically mild and transient.

Common Side Effects: - Nausea - Metallic taste - Headache - Dizziness - Diarrhea - Abdominal pain

Serious or Rare Side Effects: - Seizures - Peripheral neuropathy - Severe allergic reactions (anaphylaxis) - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Severe neutropenia or leukopenia - Hepatic dysfunction

What precautions apply to Metronidazole?

Metronidazole Braun should be used with caution in specific clinical situations. - Renal impairment: assess renal function and consider dose adjustment. - Hepatic dysfunction: monitor liver enzymes during therapy. - Alcohol consumption: avoid alcohol to prevent a disulfiram‑like reaction. - Pregnancy: prescribe only when benefits outweigh potential risks. - Concomitant warfarin therapy: monitor INR closely for increased anticoagulant effect. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

What does Metronidazole interact with?

Metronidazole Braun may interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid): - Alcohol: can cause severe disulfiram‑like reaction. - Warfarin: may increase anticoagulant effect, requiring INR monitoring. - Lithium: risk of elevated lithium levels.

Moderate Interactions (Monitor Closely): - Cimetidine: may raise metronidazole plasma concentrations. - Phenobarbital: may reduce metronidazole efficacy. - Phenytoin: may decrease therapeutic levels of metronidazole.

Frequently asked questions

What is Metronidazole Braun used for?+
Metronidazole Braun is an intravenous formulation of metronidazole indicated for the treatment of anaerobic bacterial infections, bacterial vaginosis, trichomoniasis, amebic liver abscess, and Clostridioides difficile infection. It is prescribed by qualified healthcare professionals for these conditions.
How does metronidazole work?+
Metronidazole is taken up by anaerobic microorganisms and reduced to reactive nitro radical anions. These anions bind to DNA, causing strand breakage and inhibition of nucleic acid synthesis, which ultimately kills the bacteria or protozoa while sparing aerobic cells.
What is the usual dose of Metronidazole Braun?+
The dosage of Metronidazole Braun is determined by the prescribing clinician based on the specific infection, patient weight, renal and hepatic function, and other clinical factors. No fixed regimen is provided here; the prescriber sets the appropriate dose.
Is Metronidazole Braun safe during pregnancy or breastfeeding?+
Safety data for metronidazole in pregnancy are limited, and the drug is generally classified as a category B or C agent depending on the region. It should be used only if the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult their physician, as metronidazole is excreted in breast milk.
How do I order Metronidazole Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and import documentation.
How does Metronidazole Braun compare with other antibiotics for anaerobic infections?+
Metronidazole is often preferred for anaerobic infections because of its excellent tissue penetration and activity against a broad spectrum of obligate anaerobes. Compared with clindamycin, it has a lower risk of causing Clostridioides difficile colitis, while offering similar efficacy for many intra‑abdominal and gynecologic infections.
What are the storage and handling requirements for Metronidazole Braun?+
Metronidazole Braun should be stored at 2‑8 °C in a refrigerator, protected from light. Do not freeze the product, and keep it in the original packaging to maintain stability. Once removed from refrigeration, use according to the manufacturer’s recommended time frame.
How is Metronidazole Braun administered?+
Metronidazole Braun is given by intravenous injection or infusion. The solution is typically diluted in compatible IV fluids and administered over a period specified by the prescriber, often 30‑60 minutes for a single dose. Administration should be performed by qualified healthcare personnel.
What are the most serious risks to watch for while using Metronidazole Braun?+
Serious adverse reactions include seizures, peripheral neuropathy, severe allergic responses such as anaphylaxis, Stevens‑Johnson syndrome, and significant liver injury. Patients should be monitored for neurological symptoms, skin reactions, and hepatic dysfunction, and treatment should be discontinued if any of these occur.
Who should not use Metronidazole Braun?+
Metronidazole Braun is contraindicated in individuals with a known hypersensitivity to metronidazole or other nitroimidazoles, and in patients with severe hepatic impairment. Caution is also advised for those with a history of seizures or peripheral neuropathy, and it should be avoided in patients who cannot abstain from alcohol during therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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