GNH USA

Europe — EMA

Metronidazole Biosedra

GNH USA supplies Metronidazole Biosedra (Metronidazole), a Nitroimidazole antibiotic for anaerobic bacterial infections, bacterial vaginosis, and C.

Metronidazole

Request sourcing

1
Pack/s

What is Metronidazole?

Metronidazole, the active ingredient in Metronidazole Biosedra, is a Nitroimidazole presented as an injectable solution for Intravenous use. It treats anaerobic bacterial infections and related conditions in adult patients.

GNH USA supplies Metronidazole Biosedra as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metronidazole used for?

Metronidazole Biosedra is a nitroimidazole antibiotic that targets anaerobic bacteria and protozoa.

- Anaerobic bacterial infections: eradicates susceptible anaerobes and resolves infection. - Bacterial vaginosis: restores normal vaginal flora by eliminating pathogenic anaerobes. - Trichomoniasis: eliminates Trichomonas vaginalis, relieving symptoms. - Amebic liver abscess: destroys Entamoeba histolytica trophozoites in hepatic tissue. - Clostridioides difficile infection: reduces toxin‑producing C. difficile and aids clinical recovery.

What are the side effects of Metronidazole?

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Headache: mild to moderate headache. - Diarrhea: loose stools, often self‑limited. - Abdominal pain: cramping or discomfort. - Dizziness: occasional light‑headedness.

Serious or Rare Side Effects: - Seizures: rare neurologic events. - Peripheral neuropathy: tingling or numbness in extremities. - Severe allergic reactions: anaphylaxis, rash, or swelling. - Stevens‑Johnson syndrome: severe skin and mucous membrane reaction. - Liver toxicity: elevated transaminases or hepatitis. - Neutropenia: marked reduction in white blood cells.

What precautions apply to Metronidazole?

Before using Metronidazole Biosedra, consider the following safety measures.

- Renal impairment: adjust therapy and monitor renal function. - Hepatic disease: use with caution and monitor liver enzymes. - Alcohol consumption: avoid to prevent disulfiram‑like reaction. - Pregnancy: prescribe only if benefit outweighs potential risk. - Concurrent warfarin therapy: monitor INR closely for increased anticoagulation. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Metronidazole interact with?

Metronidazole can interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid): - Alcohol: may cause severe disulfiram‑like reaction. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: heightened lithium toxicity.

Moderate Interactions (Monitor Closely): - Cimetidine: may raise metronidazole plasma levels. - Phenobarbital: may reduce metronidazole efficacy. - Phenytoin: may lower metronidazole concentrations.

Frequently asked questions

What is Metronidazole Biosedra used for?+
Metronidazole Biosedra is an intravenous nitroimidazole antibiotic indicated for the treatment of anaerobic bacterial infections, bacterial vaginosis, trichomoniasis, amebic liver abscess, and Clostridioides difficile infection. It is used in adult patients when a systemic, rapid‑acting antimicrobial is required.
How does Metronidazole work?+
Metronidazole enters anaerobic microorganisms and is reduced to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to loss of cellular function and death of the pathogen.
What is the usual dose of Metronidazole Biosedra?+
The exact dose and infusion rate are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and other clinical factors. Dosing regimens can vary widely, so the prescriber sets the appropriate schedule.
Is Metronidazole safe in pregnancy or breastfeeding?+
Metronidazole’s pregnancy category is not definitively established. It should be used during pregnancy only when the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their healthcare provider, as the drug is excreted in breast milk.
How do I order Metronidazole Biosedra from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Metronidazole compare with other antibiotics for anaerobic infections?+
Metronidazole is often preferred for anaerobic infections because of its rapid bactericidal activity, excellent tissue penetration, and oral‑to‑IV switch capability. Compared with clindamycin, it has a lower risk of Clostridioides difficile overgrowth, while offering similar efficacy against many anaerobes.
How should Metronidazole Biosedra be stored and handled?+
Store the product at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from light and moisture, and ensure the container is tightly sealed until use.
How is Metronidazole Biosedra administered?+
Metronidazole Biosedra is given by intravenous infusion. The infusion rate and duration are set by the prescriber, typically over 30–60 minutes, and the solution should be administered using aseptic technique in a clinical setting.
What are the most serious risks to watch for with Metronidazole?+
Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, liver toxicity, and neutropenia. Patients should be monitored for neurological symptoms, skin reactions, and signs of hepatic dysfunction.
Who should not use Metronidazole Biosedra?+
Metronidazole is contraindicated in individuals with a known hypersensitivity to metronidazole or other nitroimidazoles. It should be avoided in early pregnancy unless absolutely necessary, and used with caution in patients with severe hepatic impairment or those receiving concurrent alcohol.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
Fresenius Kabi France S.A.S.
Origin
EU

Related products