Metronidazole Basi

Metronidazole, the active ingredient in Metronidazole Basi, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. It treats anaerobic bacterial infections and selected protozoal infections in both adult and pediatric patients, commonly prescribed under medical supervision.

GNH USA supplies Metronidazole Basi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Clients benefit from consistent product availability and regulatory compliance across EU and international markets.

Metronidazole is a nitroimidazole antibiotic that targets anaerobic bacteria and certain protozoa.

- Anaerobic bacterial infections: eradicates susceptible anaerobes and reduces infection severity. - Bacterial vaginosis: restores normal vaginal flora by eliminating overgrowth of anaerobic organisms. - Trichomoniasis: eliminates Trichomonas vaginalis, relieving symptoms and preventing transmission. - Amebiasis: treats intestinal infection caused by Entamoeba histolytica, reducing tissue invasion. - Clostridioides difficile infection: suppresses toxin‑producing C. difficile, aiding resolution of colitis.

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea - Metallic taste - Headache - Diarrhea

Serious or Rare Side Effects: - Seizures - Severe allergic reactions (anaphylaxis) - Stevens‑Johnson syndrome - Peripheral neuropathy

Before initiating Metronidazole therapy, clinicians should consider several safety precautions.

- Assess renal function: adjust dosing in severe renal impairment. - Monitor for hypersensitivity: discontinue if severe allergic reaction occurs. - Avoid use in first trimester unless essential: limited safety data in early pregnancy. - Use with caution in hepatic disease: monitor liver enzymes during treatment. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Metronidazole can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Alcohol: may cause a disulfiram‑like reaction with flushing and nausea. - Warfarin: can increase anticoagulant effect and risk of bleeding. - Lithium: may raise lithium concentrations, leading to toxicity.

Moderate Interactions (Monitor Closely): - Cimetidine: may increase metronidazole plasma levels. - Phenytoin: may reduce metronidazole effectiveness. - Oral contraceptives: may decrease hormonal efficacy, requiring additional contraception.