Metronidazole B. Braun

Metronidazole, the active ingredient in Metronidazole B. Braun, is a nitroimidazole antibiotic presented as an injection for intravenous use. It treats anaerobic bacterial infections and certain protozoal diseases in adult and pediatric patients.

GNH USA supplies Metronidazole B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metronidazole is employed to manage infections caused by anaerobic bacteria and selected protozoa. - Anaerobic bacterial infections: effective against mixed anaerobic flora, reducing infection severity. - Bacterial vaginosis: restores normal vaginal flora by eliminating pathogenic anaerobes. - Trichomoniasis: eradicates Trichomonas vaginalis, relieving symptoms and preventing recurrence. - Amebic liver abscess: targets Entamoeba histolytica, aiding resolution of hepatic lesions. - Clostridioides difficile infection: suppresses toxin‑producing C. difficile, helping control colitis.

Metronidazole may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Metallic taste: transient metallic sensation in the mouth. - Headache: occasional mild headache. - Diarrhea: loose stools during therapy. - Abdominal pain: cramping or discomfort. - Dizziness: light‑headed feeling.

Serious or Rare Side Effects: - Seizures: rare neurologic events. - Peripheral neuropathy: tingling or numbness in extremities. - Stevens‑Johnson syndrome: severe skin reaction. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Neutropenia: low white‑blood‑cell count. - Hepatic dysfunction: elevated liver enzymes or jaundice.

Metronidazole requires careful monitoring in specific patient populations and clinical situations. - Renal function assessment: adjust use in severe renal impairment. - Hepatic function monitoring: watch for liver enzyme elevations. - Alcohol avoidance: risk of disulfiram‑like reaction. - Pregnancy safety: Category B, use only if benefits outweigh risks. - CNS disorders caution: may exacerbate seizures. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Metronidazole can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Alcohol: may cause severe flushing and tachycardia. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: heightened neurotoxicity risk.

Moderate Interactions (Monitor Closely): - Carbamazepine: may reduce metronidazole levels. - Cimetidine: can increase metronidazole plasma concentration. - Oral contraceptives: may reduce hormonal efficacy, consider backup contraception.