GNH USA

Europe — EMA

Metronidazole B. Braun

GNH USA supplies Metronidazole B. Braun (Metronidazole), a nitroimidazole antibiotic for anaerobic bacterial infections, intra‑abdominal infections

Metronidazole

Request sourcing

1
Pack/s

What is Metronidazole?

Metronidazole, the active ingredient in Metronidazole B. Braun, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal infections in adult patients.

GNH USA supplies Metronidazole B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

What is Metronidazole used for?

Metronidazole is a nitroimidazole antibiotic indicated for a range of anaerobic and protozoal infections. - Anaerobic bacterial infections: eradicates mixed anaerobic flora in deep‑tissue infections. - Intra‑abdominal infections: treats peritonitis, abscesses and postoperative intra‑abdominal sepsis. - Pelvic inflammatory disease: eliminates anaerobic organisms contributing to PID. - Bacterial vaginosis: restores normal vaginal flora by targeting Gardnerella and other anaerobes. - Clostridioides difficile‑associated diarrhea: reduces toxin‑producing C. difficile in the colon.

What are the side effects of Metronidazole?

Metronidazole may cause a variety of adverse reactions.

Common Side Effects: - Nausea - Metallic taste - Headache - Dizziness - Diarrhea - Abdominal discomfort

Serious or Rare Side Effects: - Seizures - Peripheral neuropathy - Severe allergic reactions (anaphylaxis) - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Hepatic toxicity - Neutropenia or agranulocytosis

What precautions apply to Metronidazole?

Before initiating therapy, consider the following precautions. - Renal impairment: adjust therapy based on renal function. - Hepatic dysfunction: monitor liver enzymes during treatment. - Alcohol consumption: avoid due to risk of a disulfiram‑like reaction. - Pregnancy: use only when the potential benefit justifies the potential risk to the fetus. - Concurrent use with disulfiram or alcohol‑containing products: contraindicated. - Store at controlled room temperature: keep in the original container, protect from light and moisture.

What does Metronidazole interact with?

Metronidazole can interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid): - Alcohol: may cause a severe disulfiram‑like reaction. - Warfarin: may potentiate anticoagulant effect and increase INR. - Lithium: may raise serum lithium concentrations.

Moderate Interactions (Monitor Closely): - Cimetidine: may increase metronidazole plasma levels. - Phenobarbital: may reduce metronidazole concentrations. - Erythromycin: may increase risk of neurotoxicity.

Frequently asked questions

What conditions is Metronidazole B. Braun used to treat?+
Metronidazole B. Braun is indicated for anaerobic bacterial infections, intra‑abdominal infections, pelvic inflammatory disease, bacterial vaginosis, Clostridioides difficile‑associated diarrhea, and amebic liver abscesses. It targets organisms that thrive in low‑oxygen environments and is used in adult patients when a parenteral route is required.
How does metronidazole work against microorganisms?+
Metronidazole enters anaerobic bacteria and protozoa and is reduced by intracellular electron‑transfer proteins to form nitro radicals. These reactive species damage DNA, inhibit nucleic acid synthesis, and disrupt essential metabolic pathways, resulting in irreversible cell death of the targeted microorganisms.
What determines the dosing regimen for Metronidazole B. Braun?+
The dose and duration of Metronidazole B. Braun are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and local treatment guidelines. No fixed dosing can be provided without a medical prescription.
Is Metronidazole B. Braun safe during pregnancy or breastfeeding?+
The safety of Metronidazole B. Braun in pregnancy has not been definitively established; it should be used only when the potential benefit outweighs any possible risk to the fetus. Limited data suggest it passes into breast milk, so caution is advised and breastfeeding decisions should be made with a healthcare professional.
How do I order Metronidazole B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Metronidazole compare with other antibiotics for anaerobic infections?+
Metronidazole is unique among anaerobic antibiotics because it is selectively activated within anaerobic cells, offering rapid bactericidal activity. Compared with clindamycin or beta‑lactam/beta‑lactamase inhibitor combinations, metronidazole often provides a narrower spectrum focused on anaerobes, which can reduce collateral impact on normal flora but may require combination therapy for mixed infections.
What are the recommended storage conditions for Metronidazole B. Braun?+
Metronidazole B. Braun should be stored at controlled room temperature, typically below 25 °C, in its original packaging. The container should be kept away from direct sunlight, moisture, and extreme temperature fluctuations to maintain product stability.
How is Metronidazole B. Braun administered to patients?+
Metronidazole B. Braun is supplied as an intravenous solution and is administered directly into a vein by a qualified healthcare professional. The infusion rate and concentration are set by the prescriber according to the clinical situation and patient-specific factors.
What are the most serious risks to watch for while using Metronidazole?+
Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome or toxic epidermal necrolysis, hepatic toxicity, and hematologic abnormalities like neutropenia. Patients should be monitored for neurological symptoms, skin reactions, and liver function during therapy.
Who should not receive Metronidazole B. Braun?+
Metronidazole B. Braun is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazoles, and in individuals who have consumed alcohol or are taking disulfiram due to the risk of a severe disulfiram‑like reaction. Caution is also advised for patients with severe hepatic or renal impairment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

Related products

A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU
A

A

Liquid Extract From Viscum Album Subsp. Abietis Var Abies Alba (1:20), Extraction Solvents: Water Fo

Helixor Heilmittel Gmbh
EU