Metronidazole Aurobindo

Metronidazole, the active ingredient in Metronidazole Aurobindo, is a nitroimidazole antibiotic presented as an oral tablet for systemic use. It treats a range of anaerobic bacterial and protozoal infections in adults and children as prescribed by a healthcare professional.

GNH USA supplies Metronidazole Aurobindo as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metronidazole is a nitroimidazole agent used to treat infections caused by anaerobic bacteria and certain protozoa. - Bacterial vaginosis: eradicates the anaerobic bacteria responsible for vaginal discharge and odor. - Trichomoniasis: eliminates Trichomonas vaginalis infection in the genitourinary tract. - Amoebiasis: clears intestinal Entamoeba histolytica infection and associated dysentery. - Giardiasis: treats Giardia lamblia infection causing diarrhoea. - Anaerobic bacterial infections: combats mixed‑flora infections in the abdomen, skin and oral cavity. - Clostridioides difficile infection: reduces toxin‑producing C. difficile in the colon.

Metronidazole may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Metallic taste: transient metallic sensation in the mouth. - Headache: occasional dull or throbbing headache. - Diarrhoea: loose stools that resolve after therapy.

Serious or Rare Side Effects: - Peripheral neuropathy: tingling or numbness in extremities. - Seizures: rare occurrence of convulsive episodes. - Severe allergic reaction: rash, itching, swelling, or difficulty breathing.

Before prescribing Metronidazole, clinicians should consider the following safety measures. - Liver function: assess hepatic status as the drug is metabolised hepatically. - Alcohol consumption: advise patients to avoid alcohol due to disulfiram‑like reaction. - Neurological history: monitor for signs of neuropathy, especially with prolonged use. - Pregnancy and lactation: evaluate risk‑benefit ratio; use only if clearly needed. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Metronidazole can alter the activity of several concomitant medicines.

Major Interactions (Avoid): - Disulfiram: concurrent use may cause severe flushing, tachycardia, and hypotension. - Warfarin: increased anticoagulant effect leading to heightened bleeding risk.

Moderate Interactions (Monitor Closely): - Lithium: may raise serum lithium levels; monitor renal function and lithium concentrations. - Cimetidine: can increase metronidazole plasma concentrations; observe for enhanced toxicity. - Phenytoin: may reduce phenytoin levels; adjust dosage if therapeutic monitoring indicates.