Metronidazole Accord-Uk

Metronidazole, the active ingredient in Metronidazole Accord-Uk, is a nitroimidazole antibiotic presented as an oral dosage form for oral use. It treats anaerobic bacterial and protozoal infections in adults and children as prescribed.

GNH USA supplies Metronidazole Accord-Uk as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metronidazole is a nitroimidazole antibiotic used to treat infections caused by anaerobic bacteria and certain protozoa. - Bacterial vaginosis: eradicates the anaerobic bacteria responsible for the condition. - Trichomoniasis: eliminates the protozoan parasite causing the infection. - Amoebiasis: clears intestinal Entamoeba histolytica infection. - Anaerobic infections: treats a broad range of anaerobic bacterial infections. - Clostridioides difficile infection: helps resolve toxin-mediated colitis.

Metronidazole may cause a variety of adverse reactions.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Abdominal pain: cramping or discomfort. - Diarrhea: loose stools. - Headache: mild to moderate. - Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects: - Seizures: convulsions in susceptible individuals. - Peripheral neuropathy: tingling or numbness in extremities. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Stevens-Johnson syndrome: severe skin reactions. - Pseudomembranous colitis: Clostridioides difficile overgrowth. - Hepatic dysfunction: elevated liver enzymes or jaundice.

Before using Metronidazole, consider the following safety measures. - Renal impairment: assess kidney function and adjust dose if needed. - Hepatic disease: use with caution in patients with liver dysfunction. - Alcohol consumption: avoid alcohol during treatment and for 48 hours after completion to prevent disulfiram-like reactions. - Pregnancy: consult prescriber; safety data are limited. - Concurrent warfarin therapy: monitor INR closely due to potential increased anticoagulant effect. - Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Metronidazole can interact with several medicines, requiring attention to the level of risk.

Major Interactions (Avoid): - Alcohol: may cause a disulfiram-like reaction. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: elevated lithium concentrations, risk of toxicity.

Moderate Interactions (Monitor Closely): - Cimetidine: may raise metronidazole plasma levels. - Phenobarbital: may reduce metronidazole efficacy. - Oral contraceptives: may decrease hormonal effectiveness, consider additional contraception.