Metronidazol-Human Teva Gyógyszergyár

Metronidazole, the active ingredient in Metronidazol-Human Teva Gyógyszergyár, is a nitroimidazole antibiotic presented as an intravenous solution for parenteral use. It treats anaerobic bacterial infections and selected protozoal diseases in adult patients, offering broad-spectrum activity against susceptible organisms. GNH USA supplies Metronidazol-Human Teva Gyógyszergyár as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Metronidazole acts on anaerobic bacteria and certain protozoa, making it useful for a range of infections. - Anaerobic bacterial infections: effective against infections caused by anaerobic organisms, reducing bacterial load. - Clostridioides difficile‑associated colitis: helps resolve toxin‑mediated diarrhea and colitis. - Bacterial vaginosis: restores normal vaginal flora by eliminating pathogenic anaerobes. - Trichomoniasis: eradicates Trichomonas vaginalis, relieving symptoms. - Amoebic liver abscess: targets Entamoeba histolytica in hepatic tissue. - Pelvic inflammatory disease: assists in controlling mixed anaerobic pelvic infections.

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Metallic taste: transient alteration of taste perception. - Diarrhea: loose stools, usually self‑limiting. - Abdominal pain: cramping or discomfort in the abdomen. - Headache: mild to moderate headache episodes. - Dizziness: occasional light‑headedness.

Serious or Rare Side Effects: - Severe allergic reactions: rash, itching, swelling, or anaphylaxis. - Seizures: rare neurologic events, especially with high doses. - Neutropenia: reduced white blood cell count, increasing infection risk. - Stevens‑Johnson syndrome: severe skin and mucous membrane disorder. - Hepatic dysfunction: elevated liver enzymes or jaundice. - Peripheral neuropathy: tingling or numbness in extremities.

Metronidazole requires careful use in specific clinical situations. - Renal impairment: adjust dosing and monitor renal function. - Hepatic disease: monitor liver enzymes and consider dose modification. - Alcohol consumption: avoid alcohol to prevent disulfiram‑like reactions. - Pregnancy: use only when benefits outweigh potential risks. - Concurrent warfarin therapy: monitor INR closely for increased anticoagulation. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Metronidazole can interact with several medicines, requiring vigilance.

Major Interactions (Avoid): - Alcohol: may cause severe disulfiram‑like reaction. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: elevated lithium levels, potential toxicity.

Moderate Interactions (Monitor Closely): - Phenytoin: may reduce metronidazole plasma concentrations. - Cimetidine: can increase metronidazole levels, enhancing effects. - Theophylline: possible increased theophylline toxicity.