GNH USA

Europe — EMA

Metronidazol Panpharma

GNH USA supplies Metronidazol Panpharma (Metronidazole), a nitroimidazole antibiotic for bacterial vaginosis, trichomoniasis and anaerobic infections.

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol Panpharma, is a nitroimidazole antibiotic presented as an injectable solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal diseases in adults and children as prescribed by a healthcare professional.

GNH USA supplies Metronidazol Panpharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across global markets.

What is Metronidazole used for?

Metronidazol Panpharma is a nitroimidazole antibiotic used to manage infections caused by anaerobic bacteria and susceptible protozoa. - Bacterial vaginosis: eradicates the anaerobic bacteria responsible for the condition, relieving discharge and odor. - Trichomoniasis: eliminates Trichomonas vaginalis, curing infection and preventing recurrence. - Amebic dysentery: destroys Entamoeba histolytica trophozoites, reducing intestinal inflammation and diarrhea. - Anaerobic bacterial infections: targets a broad range of anaerobes in intra‑abdominal, pelvic and skin‑soft tissue infections. - Clostridioides difficile infection: suppresses toxin‑producing C. difficile, aiding clinical resolution of severe colitis.

What are the side effects of Metronidazole?

Metronidazol Panpharma may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Headache: mild headache during treatment. - Diarrhea: loose stools that resolve after therapy.

Serious or Rare Side Effects: - Seizures: rare neurologic events requiring immediate medical attention. - Severe allergic reaction (anaphylaxis): rapid onset of hives, swelling, and breathing difficulty. - Peripheral neuropathy: tingling or numbness in extremities, potentially persistent.

What precautions apply to Metronidazole?

Metronidazol Panpharma requires careful clinical consideration before and during therapy. - Assess renal function: adjust use in patients with severe impairment. - Avoid alcohol: risk of disulfiram‑like reaction with flushing and tachycardia. - Monitor for neurotoxicity: report numbness, tingling, or gait disturbances. - Use with caution in pregnancy: category B, benefits must outweigh potential risks. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Metronidazole interact with?

Metronidazol Panpharma can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Alcohol: may cause severe disulfiram‑like reaction. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk. - Lithium: may raise lithium levels, leading to toxicity.

Moderate Interactions (Monitor Closely): - Cimetidine: can increase metronidazole plasma concentrations. - Phenytoin: may reduce metronidazole effectiveness.

Frequently asked questions

What conditions is Metronidazol Panpharma used to treat?+
Metronidazol Panpharma is indicated for bacterial vaginosis, trichomoniasis, amebic dysentery, a broad range of anaerobic bacterial infections, and Clostridioides difficile infection. It is administered intravenously under the direction of a qualified prescriber to target the responsible microorganisms.
How does metronidazole work against infections?+
Metronidazole enters anaerobic cells and is reduced to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to loss of cellular function and death of the bacteria or protozoa while sparing aerobic cells.
What is the usual dose of Metronidazol Panpharma?+
The dosage and duration of Metronidazol Panpharma are determined by the prescribing clinician based on the infection type, severity, patient weight, renal function and other clinical factors. The product is supplied as an injectable solution for intravenous administration.
Is Metronidazol Panpharma safe during pregnancy or breastfeeding?+
Metronidazol Panpharma is classified as pregnancy category B, indicating no evidence of risk in animal studies but limited human data. It may be used during pregnancy only if the potential benefit justifies the risk. Breastfeeding mothers should consult their healthcare provider, as the drug is excreted in milk.
How do I order Metronidazol Panpharma from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Metronidazol Panpharma compare with other nitroimidazole antibiotics?+
Metronidazol Panpharma shares the same class mechanism as other nitroimidazoles such as tinidazole. Compared with oral formulations, the intravenous version offers rapid systemic exposure, which is advantageous for severe or hospitalized infections where oral absorption may be unreliable.
What are the storage requirements for Metronidazol Panpharma?+
Store Metronidazol Panpharma at ambient temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from moisture and direct light, and ensure the container is tightly closed when not in use.
How is Metronidazol Panpharma administered?+
Metronidazol Panpharma is supplied as an injectable solution for intravenous infusion. Administration is performed by qualified healthcare personnel, typically diluted in an appropriate compatible IV fluid and infused over the recommended period as directed by the prescriber.
What are the most serious risks associated with Metronidazol Panpharma?+
Serious risks include seizures, severe allergic reactions such as anaphylaxis, and peripheral neuropathy that may be irreversible. Patients should be monitored for neurological symptoms, rash, or breathing difficulties, and treatment should be stopped immediately if any of these occur.
Who should not use Metronidazol Panpharma?+
Metronidazol Panpharma is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazole derivatives. It should also be avoided in individuals with a history of severe neurologic reactions to the drug.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
Panpharma Gmbh
Origin
EU

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