GNH USA

Europe — EMA

Metronidazol Jelfa

GNH USA supplies Metronidazol Jelfa (Metronidazole), a Nitroimidazole antibiotic for bacterial skin infections, rosacea and acne. Request a quote for supply.

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol Jelfa, is a Nitroimidazole antibiotic presented as a topical formulation for skin application. It is used to treat bacterial skin infections, manage rosacea, and address acne vulgaris in appropriate patients.

GNH USA supplies Metronidazol Jelfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established quality‑assurance processes and regulatory approvals across EU and other markets. The company ensures consistent batch integrity and on‑time delivery to meet global healthcare needs.

What is Metronidazole used for?

Metronidazole is employed in dermatologic conditions where anaerobic bacteria or protozoal organisms contribute to disease.

- Bacterial skin infections: eliminates anaerobic bacteria, reducing inflammation and promoting wound healing. - Rosacea: decreases inflammatory papules and erythema, improving facial appearance. - Acne vulgaris: limits Propionibacterium acnes overgrowth and associated inflammation, leading to fewer lesions.

What are the side effects of Metronidazole?

Topical metronidazole may cause local reactions, though most are mild and reversible.

Common Side Effects: - Skin irritation: mild redness or discomfort at the application site. - Dryness or peeling of the skin. - Burning or stinging sensation during or after application. - Itching or mild pruritus. - Contact dermatitis: localized allergic rash.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis) with swelling, difficulty breathing, or hives. - Stevens‑Johnson syndrome or toxic epidermal necrolysis presenting as extensive skin blistering. - Significant ulceration or necrosis of the treated area. - Systemic toxicity if large surface areas are applied, leading to neurological symptoms. - Unexplained fever or malaise indicating systemic involvement.

What precautions apply to Metronidazole?

When using Metronidazol Jelfa, consider the following safety measures.

- Pregnancy: consult a healthcare provider; safety data are limited. - Breastfeeding: avoid use unless the benefit to the mother outweighs potential risk to the infant. - Known hypersensitivity: discontinue immediately if an allergic reaction occurs. - Extensive application area: monitor for signs of systemic absorption such as dizziness or neuropathy. - Open wounds or mucous membranes: avoid application unless specifically directed by a prescriber. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct light.

What does Metronidazole interact with?

Metronidazol Jelfa can affect or be affected by other medicines; review the following interactions.

Major Interactions (Avoid): - Alcohol: may cause a disulfiram‑like reaction with flushing, nausea, and tachycardia. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk. - Lithium: may raise serum lithium levels, leading to toxicity.

Moderate Interactions (Monitor Closely): - Oral contraceptives: may reduce hormonal efficacy, requiring additional contraceptive measures. - Phenytoin: potential for increased neurotoxic side effects. - Tetracyclines: possible antagonistic effect reducing antibacterial activity.

Frequently asked questions

What conditions is Metronidazol Jelfa used for?+
Metronidazol Jelfa is a topical formulation of metronidazole indicated for bacterial skin infections, rosacea, and acne vulgaris. It works by targeting anaerobic bacteria and inflammatory processes in the skin, helping to reduce lesions, redness, and infection.
How does metronidazole work in this product?+
Metronidazole is converted inside anaerobic microorganisms into reactive nitro radicals that damage DNA and inhibit nucleic acid synthesis. This leads to bacterial cell death and reduces protozoal activity, providing antibacterial and antiprotozoal effects at the site of application.
What is the usual dose of Metronidazol Jelfa?+
The specific dose and frequency of Metronidazol Jelfa are determined by the prescribing healthcare professional based on the patient’s condition, severity, and treatment goals. Patients should follow the prescriber’s instructions and not alter the regimen on their own.
Is Metronidazol Jelfa safe during pregnancy or breastfeeding?+
Safety data for topical metronidazole in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using this product.
How do I order Metronidazol Jelfa from GNH USA?+
To request Metronidazol Jelfa, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Metronidazol Jelfa compare with other acne treatments?+
Compared with oral antibiotics, topical metronidazole offers localized action with minimal systemic exposure, reducing the risk of systemic side effects. It is particularly useful for inflammatory lesions and for patients who cannot tolerate oral agents, though it may be less potent for severe cystic acne.
What are the storage and handling requirements for Metronidazol Jelfa?+
Metronidazol Jelfa should be stored at ambient temperature, preferably below 25 °C, in its original container. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations to maintain its stability and efficacy.
How is Metronidazol Jelfa applied?+
The product is applied topically to the affected skin area, typically once or twice daily as directed by a healthcare professional. Clean and dry the skin before application, and avoid contact with eyes, mucous membranes, or open wounds unless specifically instructed.
What are the most serious risks associated with Metronidazol Jelfa?+
Serious risks include severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and extensive skin ulceration. If any signs of severe rash, blistering, swelling, or systemic symptoms occur, discontinue use and seek immediate medical attention.
Who should not use Metronidazol Jelfa?+
Individuals with a known hypersensitivity to metronidazole or any component of the formulation should avoid using Metronidazol Jelfa. It is also contraindicated on extensive open wounds, mucous membranes, or in patients where systemic absorption could pose a risk without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Cutaneous Use
Manufacturer
Bausch Health Ireland Limited
Origin
EU

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