GNH USA

Europe — EMA

Metronidazol Hikma

GNH USA supplies Metronidazol Hikma (Metronidazole), a nitroimidazole antibiotic for bacterial vaginosis, intra‑abdominal infections and other anaerobic

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol Hikma, is a nitroimidazole antibiotic presented as an injectable solution for intravenous use. It is marketed in the European Union and indicated for infections such as bacterial vaginosis, trichomoniasis and intra‑abdominal infections in adult patients.

GNH USA supplies Metronidazol Hikma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution channels across Europe, Asia and the Americas.

What is Metronidazole used for?

Metronidazole is a nitroimidazole antibiotic used to treat infections caused by anaerobic bacteria and certain protozoa. - Bacterial vaginosis: eradicates the anaerobic bacteria responsible for the condition, reducing symptoms. - Trichomoniasis: eliminates the protozoan parasite, relieving vaginal discharge and irritation. - Anaerobic bacterial infections: provides bactericidal activity against a broad range of anaerobes. - Intra‑abdominal infections: controls polymicrobial infections following surgery or perforation. - Pelvic inflammatory disease: treats mixed anaerobic infections contributing to PID. - Clostridioides difficile infection: reduces toxin‑producing bacteria in the colon.

What are the side effects of Metronidazole?

Metronidazole may cause a range of adverse reactions, from mild to severe.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Headache: occasional throbbing or pressure headache. - Diarrhea: loose stools that may be watery. - Abdominal pain: cramping or discomfort in the abdomen. - Dizziness: light‑headed feeling, especially when standing.

Serious or Rare Side Effects: - Seizures: rare neurologic events requiring immediate care. - Peripheral neuropathy: tingling or numbness in extremities. - Severe allergic reactions: anaphylaxis with rash, swelling, or breathing difficulty. - Stevens‑Johnson syndrome: serious skin blistering and detachment. - Neutropenia: marked reduction in white blood cells. - Hepatic dysfunction: elevated liver enzymes or jaundice.

What precautions apply to Metronidazole?

Before using Metronidazol Hikma, consider the following safety measures. - Renal impairment: assess kidney function and adjust therapy if necessary. - Hepatic dysfunction: monitor liver enzymes during treatment. - Alcohol consumption: avoid alcohol to prevent a disulfiram‑like reaction. - Pregnancy: prescribe only when benefits outweigh potential risks. - Concurrent warfarin therapy: monitor INR closely for increased anticoagulation. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Metronidazole interact with?

Metronidazol Hikma can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid): - Alcohol: may cause severe disulfiram‑like reaction. - Warfarin: can increase anticoagulant effect, raising bleeding risk. - Lithium: may raise lithium serum concentrations.

Moderate Interactions (Monitor Closely): - Cimetidine: may elevate metronidazole plasma levels. - Phenobarbital: may reduce metronidazole efficacy. - Bupropion: may increase seizure risk when combined.

Frequently asked questions

What conditions is Metronidazol Hikma used for?+
Metronidazol Hikma is indicated for a range of anaerobic bacterial and protozoal infections, including bacterial vaginosis, trichomoniasis, intra‑abdominal infections, pelvic inflammatory disease, and Clostridioides difficile infection. It targets organisms that thrive in low‑oxygen environments.
How does metronidazole work against infections?+
Metronidazole is taken up by anaerobic microorganisms and reduced to reactive nitro radicals. These radicals bind to DNA, causing strand breakage and inhibiting nucleic acid synthesis, which leads to bacterial or protozoal cell death while sparing most aerobic cells.
What is the usual dose of Metronidazol Hikma?+
The dosage regimen for Metronidazol Hikma is determined by the prescribing clinician based on the specific infection, patient weight, renal and hepatic function, and local treatment guidelines. Only a qualified health professional should set the dose.
Is Metronidazol Hikma safe during pregnancy or breastfeeding?+
Safety data for Metronidazol Hikma in pregnancy are limited. It should be used only if the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their physician, as the drug can be excreted in milk.
How do I order Metronidazol Hikma from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metronidazol Hikma compare with other nitroimidazole antibiotics?+
Metronidazol Hikma shares the same class mechanism as other nitroimidazoles such as tinidazole, offering comparable anaerobic coverage. Differences may lie in pharmacokinetic profiles, dosing frequency, and specific regulatory approvals, which clinicians consider when selecting therapy.
What are the storage requirements for Metronidazol Hikma?+
Metronidazol Hikma should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations to maintain stability.
How is Metronidazol Hikma administered?+
Metronidazol Hikma is administered intravenously by a qualified healthcare professional. The solution is infused into a vein over a prescribed period, following aseptic technique and appropriate infusion equipment.
What are the most serious risks associated with Metronidazol Hikma?+
Serious risks include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, neutropenia, and hepatic dysfunction. Patients should be monitored for neurological symptoms, skin changes, or signs of liver injury during therapy.
Who should not use Metronidazol Hikma?+
Metronidazol Hikma is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazole derivatives. Caution is also advised for individuals with severe hepatic impairment, and it should be avoided in those with a history of severe disulfiram‑like reactions to alcohol.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
Hikma Farmacêutica (Portugal), S.A.
Origin
EU

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