GNH USA

Europe — EMA

Metronidazol Bradex

GNH USA supplies Metronidazol Bradex (Metronidazole), a nitroimidazole antibiotic for anaerobic bacterial infections, amoebiasis and bacterial vaginosis.

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol Bradex, is a nitroimidazole antibiotic presented as an injectable solution for intravenous use. It treats anaerobic bacterial infections and certain protozoal diseases in adult and pediatric patients when indicated by a prescriber.

GNH USA supplies Metronidazol Bradex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Metronidazole used for?

Metronidazol Bradex is a nitroimidazole antibiotic used to target anaerobic microorganisms and protozoa.

- Anaerobic bacterial infections: eradicates mixed anaerobic flora, reducing infection severity. - Amoebiasis: eliminates Entamoeba histolytica trophozoites, aiding resolution of intestinal disease. - Bacterial vaginosis: restores normal vaginal flora by suppressing anaerobic overgrowth. - Clostridioides difficile infection: controls toxin‑producing anaerobes in the colon. - Trichomoniasis: destroys Trichomonas vaginalis, relieving symptoms and preventing transmission.

What are the side effects of Metronidazole?

Metronidazol Bradex may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient alteration of taste perception. - Headache: occasional dull or throbbing pain. - Diarrhea: loose stools that may be self‑limiting.

Serious or Rare Side Effects: - Seizures: rare neurologic events requiring immediate care. - Peripheral neuropathy: tingling or numbness, especially with prolonged use. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Hepatotoxicity: elevated liver enzymes or jaundice. - Stevens‑Johnson syndrome: severe skin blistering. - Pancytopenia: reduction in blood cell counts.

What precautions apply to Metronidazole?

Before using Metronidazol Bradex, consider the following safety measures.

- Renal impairment: adjust therapy if kidney function is reduced. - Hepatic impairment: monitor liver function tests during treatment. - Alcohol consumption: avoid alcohol to prevent disulfiram‑like reactions. - Pregnancy: use only if potential benefit justifies potential risk; data are limited. - Lactation: weigh benefits against possible infant exposure. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

What does Metronidazole interact with?

Metronidazol Bradex can interact with several medicines.

Major Interactions (Avoid): - Alcohol: may cause severe flushing, nausea, and tachycardia. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: heightened lithium toxicity, monitor serum levels.

Moderate Interactions (Monitor Closely): - Phenytoin: reduced phenytoin concentrations, may require dose adjustment. - Cimetidine: increased metronidazole plasma levels, watch for toxicity.

Frequently asked questions

What is Metronidazol Bradex used for?+
Metronidazol Bradex is an intravenous formulation of metronidazole indicated for the treatment of anaerobic bacterial infections, amoebiasis, bacterial vaginosis, Clostridioides difficile infection, and trichomoniasis. It is prescribed when these infections are confirmed or strongly suspected and when oral therapy is not appropriate.
How does metronidazole work?+
Metronidazole is reduced inside anaerobic microorganisms, forming nitro radicals that damage DNA and inhibit nucleic acid synthesis. This disruption leads to loss of cellular function and ultimately death of the susceptible bacteria or protozoa.
What is the usual dose of Metronidazol Bradex?+
The specific dose and duration of Metronidazol Bradex are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and other individual factors. No standard dosing is provided here.
Is Metronidazol Bradex safe during pregnancy or breastfeeding?+
Safety data for Metronidazol Bradex in pregnancy are limited, and the product is classified as pregnancy category unknown. It should be used only if the potential benefit outweighs the potential risk. Breastfeeding mothers should consult a healthcare professional, as the drug may be excreted in milk.
How do I order Metronidazol Bradex from GNH USA?+
To order Metronidazol Bradex, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and required import documentation.
How does Metronidazol Bradex compare with other nitroimidazole antibiotics?+
Metronidazol Bradex delivers metronidazole intravenously, offering rapid systemic exposure compared with oral nitroimidazoles such as tinidazole or ornidazole. IV administration is advantageous for severe infections, patients unable to take oral medication, or when high plasma concentrations are required quickly.
How should Metronidazol Bradex be stored and handled?+
Metronidazol Bradex must be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before administration, inspect for particulate matter and ensure the solution is at room temperature if required by the clinical protocol.
How is Metronidazol Bradex administered?+
Metronidazol Bradex is given by intravenous infusion or injection under the supervision of a qualified healthcare professional. The infusion rate and dilution are determined by the prescriber and institutional guidelines to achieve the desired therapeutic concentration while minimizing adverse effects.
What are the most serious risks to watch for with Metronidazol Bradex?+
Serious risks include seizures, peripheral neuropathy, severe allergic reactions (including anaphylaxis), Stevens‑Johnson syndrome, hepatotoxicity, and pancytopenia. Patients should be monitored for neurological symptoms, skin changes, liver function abnormalities, and blood count alterations throughout therapy.
Who should not use Metronidazol Bradex?+
Metronidazol Bradex should be avoided in patients with known hypersensitivity to metronidazole or other nitroimidazoles, those with severe hepatic impairment where benefit does not outweigh risk, and individuals who cannot abstain from alcohol during treatment due to the risk of a disulfiram‑like reaction.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
Bradex S.A.
Origin
EU

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