GNH USA

Europe — EMA

Metronidazol B. Braun

GNH USA supplies Metronidazol B. Braun (Metronidazole), a nitroimidazole antibiotic for anaerobic bacterial and protozoal infections such as intra‑abdominal

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol B. Braun, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. It is employed to treat anaerobic bacterial infections and certain protozoal diseases in adult patients, including intra‑abdominal infections, pelvic inflammatory disease and bacterial vaginosis.

GNH USA supplies Metronidazol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for sterile injectable antibiotics.

What is Metronidazole used for?

Metronidazol B. Braun is a nitroimidazole antibiotic that targets anaerobic bacteria and susceptible protozoa. It is indicated for several established infections: - Intra‑abdominal infections: eradicates anaerobic organisms responsible for peritonitis and postoperative intra‑abdominal sepsis. - Pelvic inflammatory disease: treats mixed aerobic‑anaerobic infections of the upper genital tract. - Bacterial vaginosis: restores normal vaginal flora by eliminating Gardnerella and other anaerobes. - Amoebiasis: eliminates Entamoeba histolytica trophozoites in intestinal and extra‑intestinal disease.

What are the side effects of Metronidazole?

Metronidazol B. Braun may cause a range of adverse reactions. Monitoring patients for both common and serious events is recommended.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient dysgeusia during infusion. - Headache: mild to moderate intensity. - Diarrhea: loose stools, usually self‑limited.

Serious or Rare Side Effects: - Seizures: rare neurologic events requiring immediate attention. - Peripheral neuropathy: tingling or numbness, potentially irreversible. - Severe allergic reactions: anaphylaxis, angioedema, or urticaria. - Stevens‑Johnson syndrome: extensive skin and mucosal involvement.

What precautions apply to Metronidazole?

Before initiating therapy, clinicians should consider several safety factors. - Renal impairment: adjust dosing or monitor renal function closely. - Hepatic dysfunction: evaluate liver enzymes and consider dose modification. - Alcohol consumption: avoid during treatment and for 48 hours after to prevent disulfiram‑like reactions. - Pregnancy: prescribe only when benefits outweigh potential risks. - Concomitant metronidazole‑containing products: avoid duplicate therapy. - Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Metronidazole interact with?

Metronidazol B. Braun can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Alcohol: may cause severe disulfiram‑like reaction. - Warfarin: potentiates anticoagulant effect; monitor INR closely. - Lithium: can increase lithium concentrations; monitor serum levels.

Moderate Interactions (Monitor Closely): - Phenytoin: may reduce metronidazole levels, decreasing efficacy. - Cimetidine: may raise metronidazole concentrations, increasing toxicity risk.

Frequently asked questions

What is Metronidazol B. Braun used for?+
Metronidazol B. Braun is an intravenous formulation of metronidazole used to treat serious anaerobic bacterial infections such as intra‑abdominal sepsis, pelvic inflammatory disease, bacterial vaginosis, and certain protozoal infections like amoebiasis. It is administered in hospital settings where rapid, systemic therapy is required.
How does metronidazole work?+
Metronidazole is taken up by anaerobic microorganisms and reduced to reactive nitro radicals. These radicals damage DNA and inhibit nucleic acid synthesis, leading to cell death. The selective reduction occurs mainly in anaerobic cells, sparing most aerobic human tissues.
What is the usual dose of Metronidazol B. Braun?+
The specific dose and infusion rate are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and local treatment guidelines. Healthcare professionals should follow the recommended dosing regimen on the product label or institutional protocol.
Is Metronidazol B. Braun safe in pregnancy or breastfeeding?+
Safety data are limited; metronidazole is generally classified as a drug to be used in pregnancy only when the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should consult their physician before use.
How do I order Metronidazol B. Braun from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Metronidazol B. Braun compare with other treatments for anaerobic infections?+
Metronidazole is a first‑line nitroimidazole with broad activity against anaerobes and certain protozoa. Alternatives such as clindamycin or carbapenems may be used when resistance or intolerance to metronidazole occurs. Compared with tinidazole, metronidazole has a longer clinical history and more extensive safety data, though tinidazole offers a longer half‑life allowing less frequent dosing.
What are the storage and handling requirements for Metronidazol B. Braun?+
The product should be stored refrigerated at 2‑8 °C, protected from light, and must not be frozen or shaken. Before administration, allow the solution to reach room temperature if required, and inspect for particulate matter or discoloration.
How is Metronidazol B. Braun given or administered?+
Metronidazol B. Braun is administered intravenously by slow infusion under aseptic conditions. The infusion rate and total daily dose are set by the treating physician, and the medication may be given as a single daily dose or divided doses depending on the clinical scenario.
What are the most serious risks to watch for while using Metronidazol B. Braun?+
Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, and rare skin disorders like Stevens‑Johnson syndrome. Patients should be monitored for neurological symptoms, rash, or signs of hypersensitivity, and therapy should be discontinued if any of these occur.
Who should not use Metronidazol B. Braun?+
Metronidazol B. Braun is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazoles. Caution is also advised for individuals with severe hepatic impairment, those receiving disulfiram, or patients with a history of seizures or peripheral neuropathy, unless the benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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