GNH USA

Europe — EMA

Metronidazol B. Braun

GNH USA supplies Metronidazol B. Braun (Metronidazole), a nitroimidazole antibiotic for anaerobic bacterial infections and related conditions.

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol B. Braun, is a nitroimidazole antibiotic presented as an intravenous solution for intravenous use. Originating from the EU market, it is indicated for the treatment of anaerobic bacterial infections, intra‑abdominal infections, pelvic inflammatory disease, bacterial vaginosis, trichomoniasis and Clostridioides difficile‑associated diarrhea in adults and children.

GNH USA supplies Metronidazol B. Braun as a licensed, GDP‑compliant international pharmaceutical supplier, delivering the product to hospitals, transplant centres and pharmacies worldwide.

What is Metronidazole used for?

Metronidazol B. Braun (metronidazole) is used to manage infections caused by anaerobic bacteria and certain protozoa. - Anaerobic bacterial infections: eradicates susceptible anaerobic organisms, reducing infection severity. - Intra‑abdominal infections: part of combination therapy for peritonitis and intra‑abdominal abscesses. - Pelvic inflammatory disease: eliminates anaerobic pathogens contributing to PID. - Bacterial vaginosis: restores normal vaginal flora by targeting Gardnerella and other anaerobes. - Trichomoniasis: eliminates Trichomonas vaginalis, relieving symptoms and preventing transmission.

What are the side effects of Metronidazole?

Metronidazol B. Braun may cause adverse reactions that vary in frequency and severity.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Headache: mild to moderate head discomfort. - Diarrhea: loose stools during therapy.

Serious or Rare Side Effects: - Seizures: convulsions requiring immediate medical attention. - Peripheral neuropathy: tingling or numbness in extremities. - Severe allergic reactions (anaphylaxis): rash, swelling, breathing difficulty. - Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.

What precautions apply to Metronidazole?

When using Metronidazol B. Braun, consider the following precautions: - Renal impairment: monitor renal function and adjust therapy as clinically indicated. - Pregnancy: category B; use only if potential benefits justify the risk. - Alcohol consumption: avoid concurrent alcohol to prevent a disulfiram‑like reaction. - Blood dyscrasias: observe complete blood counts during prolonged treatment. - Neurologic symptoms: discontinue if seizures or neuropathy develop. - Store at room temperature: keep in the original container, protect from light and moisture.

What does Metronidazole interact with?

Metronidazol B. Braun can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid): - Alcohol: may cause severe disulfiram‑like reaction. - Warfarin: may enhance anticoagulant effect, increasing bleeding risk. - Lithium: may raise lithium concentrations, leading to toxicity.

Moderate Interactions (Monitor Closely): - Cimetidine: may increase metronidazole plasma levels. - Phenobarbital: may reduce metronidazole efficacy. - Oral contraceptives: may decrease hormonal effectiveness, consider backup contraception.

Frequently asked questions

What is Metronidazol B. Braun used for?+
Metronidazol B. Braun is an intravenous formulation of metronidazole used to treat infections caused by anaerobic bacteria and certain protozoa. Indications include intra‑abdominal infections, pelvic inflammatory disease, bacterial vaginosis, trichomoniasis, and Clostridioides difficile‑associated diarrhea.
How does metronidazole work?+
Metronidazole is reduced inside anaerobic microorganisms, producing reactive nitro radicals that damage DNA and inhibit nucleic acid synthesis. This selective activation in low‑oxygen environments leads to bacterial and protozoal cell death while sparing most human cells.
What is the usual dose of Metronidazol B. Braun?+
The appropriate dose of Metronidazol B. Braun is determined by the prescribing clinician based on the specific infection, patient weight, renal and hepatic function, and other clinical factors. Dosage regimens are individualized and should follow local prescribing guidelines.
Is Metronidazol B. Braun safe in pregnancy or breastfeeding?+
Metronidazol B. Braun is classified as pregnancy category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during pregnancy only if the potential benefit outweighs any risk. Metronidazole is excreted in breast milk; caution is advised and breastfeeding decisions should be made with a healthcare professional.
How do I order Metronidazol B. Braun from GNH USA?+
To order Metronidazol B. Braun, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Metronidazol B. Braun compare with other nitroimidazoles?+
Metronidazol B. Braun shares the same class mechanism as other nitroimidazoles such as tinidazole, but metronidazole has a longer history of clinical use and a broader spectrum against anaerobic bacteria and protozoa. Tinidazole may require less frequent dosing, while metronidazole is often preferred for severe intra‑abdominal infections due to extensive clinical data.
What are the storage and handling requirements for Metronidazol B. Braun?+
Metronidazol B. Braun should be stored at room temperature, protected from light and moisture, and kept in its original packaging. Do not freeze the solution. Before administration, inspect the vial for particulate matter and ensure proper aseptic technique during preparation.
How is Metronidazol B. Braun administered?+
Metronidazol B. Braun is given by intravenous infusion. The solution is typically diluted in compatible IV fluids and infused over a period determined by the prescribing clinician, usually ranging from 30 minutes to several hours, depending on the infection severity and patient tolerance.
What are the most serious risks associated with Metronidazol B. Braun?+
Serious adverse events include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, and rare skin conditions like Stevens‑Johnson syndrome. Patients should be monitored for neurologic changes, rash, or breathing difficulties, and therapy should be stopped immediately if any of these occur.
Who should not use Metronidazol B. Braun?+
Metronidazol B. Braun is contraindicated in individuals with a known hypersensitivity to metronidazole or other nitroimidazole compounds. Caution is also advised in patients with severe hepatic impairment, and it should be avoided in those with a history of seizures unless the benefits clearly outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
B.Braun Melsungen Ag
Origin
EU

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