GNH USA

Europe — EMA

Metronidazol Altan

GNH USA supplies Metronidazol Altan (Metronidazole), a nitroimidazole antibiotic for anaerobic bacterial and protozoal infections. Request a quote for supply.

Metronidazole

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What is Metronidazole?

Metronidazole, the active ingredient in Metronidazol Altan, is a nitroimidazole antibiotic presented as an injectable solution for intravenous use. It treats anaerobic bacterial and protozoal infections in adults and children as prescribed by a qualified health professional.

GNH USA supplies Metronidazol Altan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metronidazole used for?

Metronidazol Altan is employed to manage infections caused by anaerobic microorganisms and certain protozoa.

- Intra‑abdominal infections: eliminates anaerobic bacteria and supports recovery after surgery or perforation. - Pelvic inflammatory disease: eradicates causative anaerobes and improves pelvic health. - Bacterial sepsis caused by susceptible anaerobes: provides rapid systemic antimicrobial action. - Skin and soft‑tissue infections with anaerobic involvement: reduces bacterial load and promotes wound healing. - Bone and joint infections (osteomyelitis) with anaerobic pathogens: assists in infection control and tissue repair.

What are the side effects of Metronidazole?

Metronidazol Altan may cause a range of adverse reactions, most of which are dose‑related and reversible upon discontinuation.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Headache: mild to moderate cephalgia. - Diarrhea: loose stools, usually self‑limiting. - Abdominal pain: cramping or discomfort. - Dizziness: occasional light‑headedness.

Serious or Rare Side Effects: - Seizures: rare neurologic events, especially with high doses. - Peripheral neuropathy: tingling or numbness in extremities. - Stevens‑Johnson syndrome: severe skin reactions. - Anaphylaxis: acute allergic response requiring emergency care. - Hepatic toxicity: elevated liver enzymes or hepatitis. - Severe neutropenia: marked reduction in white blood cells.

What precautions apply to Metronidazole?

Metronidazol Altan requires careful consideration of patient‑specific factors and proper handling to ensure safety. - Renal impairment: adjust dose or monitor renal function closely. - Hepatic dysfunction: use with caution; monitor liver enzymes. - Alcohol consumption: avoid due to disulfiram‑like reaction. - Hematologic disorders: watch for neutropenia or thrombocytopenia. - Pregnancy and breastfeeding: assess risk‑benefit; limited data available. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Metronidazole interact with?

Metronidazol Altan can influence or be influenced by several concomitant medicines.

Major Interactions (Avoid): - Alcohol: may cause severe flushing, tachycardia, and hypotension. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk. - Lithium: may raise lithium serum levels, leading to toxicity. - Carbamazepine: reduces metronidazole concentrations, diminishing efficacy.

Moderate Interactions (Monitor Closely): - Phenytoin: may lower metronidazole levels; monitor therapeutic response. - Phenobarbital: similar enzyme‑inducing effect as phenytoin. - Rifampin: decreases metronidazole exposure; adjust dose if needed. - Oral contraceptives: may reduce hormonal efficacy; advise additional contraception. - Cyclosporine: can increase cyclosporine concentrations; monitor renal function.

Frequently asked questions

What is Metronidazol Altan used for?+
Metronidazol Altan is an intravenous formulation of metronidazole, a nitroimidazole antibiotic used to treat severe infections caused by anaerobic bacteria and certain protozoa. It is commonly prescribed for intra‑abdominal infections, pelvic inflammatory disease, septicemia, and other serious anaerobic infections when rapid systemic therapy is required.
How does metronidazole work?+
Metronidazole enters susceptible anaerobic microorganisms and is reduced to reactive nitro radicals. These radicals interact with DNA, causing strand breakage and inhibiting nucleic acid synthesis, which leads to cell death. Aerobic cells lack the necessary reduction environment, so they are largely unaffected.
What is the usual dose of Metronidazol Altan?+
The specific dose and infusion rate of Metronidazol Altan are determined by the prescribing clinician based on the infection type, severity, patient weight, renal and hepatic function, and other clinical factors. Healthcare professionals should follow local guidelines and the product’s prescribing information.
Is Metronidazol Altan safe during pregnancy or breastfeeding?+
Safety data for Metronidazol Altan in pregnancy and lactation are limited. The prescriber must weigh potential benefits against possible risks to the fetus or infant. If treatment is essential, it may be used under close medical supervision, but alternative agents are preferred when possible.
How do I order Metronidazol Altan from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.
How does Metronidazol Altan compare with other antibiotics for anaerobic infections?+
Metronidazol Altan is a nitroimidazole that specifically targets anaerobic organisms, offering rapid bactericidal activity. Compared with broad‑spectrum agents like clindamycin or beta‑lactam/beta‑lactamase inhibitor combinations, metronidazole provides a focused mechanism with a well‑established safety profile, though resistance patterns and infection site may influence drug choice.
What are the storage and handling requirements for Metronidazol Altan?+
Metronidazol Altan should be stored at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture and direct light, and avoid freezing. Inspect the solution for particulate matter before administration.
How is Metronidazol Altan administered?+
Metronidazol Altan is administered intravenously by a qualified healthcare professional. It is typically given as an infusion over a prescribed period, often diluted in compatible IV fluids. Administration details, including infusion rate and duration, are determined by the treating physician based on clinical guidelines.
What are the most serious risks associated with Metronidazol Altan?+
Serious adverse events, though rare, include seizures, peripheral neuropathy, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, hepatic toxicity, and profound neutropenia. Patients should be monitored for neurological symptoms, skin reactions, and changes in liver function during therapy.
Who should not use Metronidazol Altan?+
Metronidazol Altan is contraindicated in patients with a known hypersensitivity to metronidazole or other nitroimidazole compounds. Caution is advised for individuals with severe hepatic or renal impairment, those receiving disulfiram, and patients with a history of neurologic disorders that could be exacerbated by the drug.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metronidazole
Route
Intravenous Use
Manufacturer
Altan Pharmaceuticals S.A.
Origin
EU

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