Metronidazol Actavis

Metronidazole, the active ingredient in Metronidazol Actavis, is a nitroimidazole antibiotic presented as an oral dosage form for oral use. It treats infections caused by anaerobic bacteria and certain protozoa in adults and children as prescribed.

GNH USA supplies Metronidazol Actavis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metronidazole is used to treat infections caused by anaerobic bacteria and protozoa.

- Bacterial vaginosis: eliminates anaerobic bacteria to restore normal vaginal flora. - Trichomoniasis: eradicates Trichomonas vaginalis, relieving symptoms. - Amoebiasis: destroys Entamoeba histolytica trophozoites in intestinal disease. - Giardiasis: clears Giardia lamblia infection from the gastrointestinal tract. - Anaerobic bacterial infections: targets a broad range of anaerobes in tissue infections. - Clostridioides difficile infection: reduces toxin‑producing C. difficile in the colon.

Metronidazole may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Metallic taste: transient metallic sensation in the mouth. - Headache: occasional dull or throbbing head pain. - Diarrhea: loose stools during treatment.

Serious or Rare Side Effects: - Seizures: rare neurologic events requiring immediate care. - Peripheral neuropathy: tingling or numbness in extremities. - Severe allergic reactions: rash, swelling, or anaphylaxis. - Liver toxicity: elevated enzymes or jaundice. - Blood dyscrasias: abnormal blood counts such as neutropenia.

Before using Metronidazol Actavis, consider the following safety measures.

- Pregnancy: consult a healthcare provider as safety data are limited. - Breastfeeding: evaluate risk versus benefit; metronidazole may pass into milk. - Alcohol consumption: avoid alcohol to prevent a disulfiram‑like reaction. - Liver disease: dose adjustment or monitoring may be required. - Renal impairment: monitor renal function and adjust dose if needed. - Store at ambient temperature: keep in the original container, protect from moisture and light.

Metronidazol Actavis can interact with several medicines; awareness helps prevent reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Alcohol: may cause severe nausea, vomiting, and flushing. - Warfarin: can potentiate anticoagulant effect, increasing bleeding risk. - Lithium: may raise lithium concentrations, leading to toxicity. - Cimetidine: can increase metronidazole plasma levels.

Moderate Interactions (Monitor Closely): - Phenobarbital: may lower metronidazole concentrations, reducing effectiveness. - Phenytoin: can decrease metronidazole levels. - Oral contraceptives: may reduce hormonal efficacy, requiring additional contraception.