Metrolotion

Metronidazole, the active ingredient in Metrolotion, is a Nitroimidazole presented as a topical preparation for topical use. It treats infections caused by susceptible anaerobic bacteria and certain protozoa, primarily on skin and mucous membranes. It is commonly employed in the management of rosacea, bacterial vaginosis, and localized skin infections, and is indicated for use in adult patients.

GNH USA supplies Metrolotion as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metronidazole is a Nitroimidazole antibiotic used for infections of the skin and mucous membranes caused by susceptible anaerobic organisms. - Rosacea: reduces inflammatory lesions and facial erythema in adult patients. - Bacterial vaginosis: eliminates anaerobic bacteria to restore normal vaginal flora when applied as a topical gel. - Localized skin infections: treats infected wounds, ulcerations and dermatitis caused by susceptible anaerobes.

Metronidazole may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Skin irritation: redness, burning or stinging at the application site. - Itching or pruritus. - Dryness or peeling of the treated skin. - Mild rash localized to the area of use.

Serious or Rare Side Effects: - Allergic reactions: urticaria, swelling, or anaphylaxis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Severe skin necrosis or ulceration. - Photosensitivity leading to exaggerated sunburn. - Systemic toxicity if extensive absorption occurs.

When using Metrolotion, consider the following safety measures. - Hypersensitivity: discontinue if signs of allergic reaction appear. - Extensive broken skin: avoid application on large open wounds. - Pregnancy: use only if clearly needed and prescribed by a healthcare professional. - Breastfeeding: consult a physician before use. - Eyes: keep product away from the ocular area. - Store at room temperature: keep in the original packaging, protect from moisture and light.

Metrolotion may interact with other medicines; some interactions require avoidance while others need monitoring.

Major Interactions (Avoid): - Alcohol: may cause a disulfiram‑like reaction with flushing and nausea. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: heightened lithium toxicity. - Cimetidine: elevated metronidazole plasma levels. - Phenytoin: reduced efficacy of phenytoin.

Moderate Interactions (Monitor Closely): - Oral contraceptives: possible reduction in contraceptive effectiveness. - Carbamazepine: may lower metronidazole concentrations. - Rifampin: enzyme induction may decrease metronidazole levels.