Metrogel

Metronidazole, the active ingredient in Metrogel, is a nitroimidazole antibiotic presented as a gel for topical (cutaneous) use. It treats inflammatory skin conditions such as rosacea in adults. GNH USA supplies Metrogel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metrogel contains metronidazole, a nitroimidazole that acts on skin inflammation and microbial colonisation associated with rosacea. - Rosacea: reduces inflammatory papules, pustules and persistent facial erythema.

Topical metronidazole gel may cause local skin reactions.

Common Side Effects: - Burning sensation at the application site - Stinging or tingling feeling - Dryness or flaking of the skin - Itching or mild pruritus - Redness or mild erythema - Peeling or scaling

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angio‑edema, anaphylaxis) - Contact dermatitis with extensive rash - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Persistent ulceration or necrosis of the skin - Systemic absorption leading to gastrointestinal upset (very rare)

Before using Metrogel, consider the following safety points. - Pregnancy: consult a healthcare professional before use. - Breastfeeding: discuss potential risks with a physician. - Broken or ulcerated skin: avoid application on compromised skin. - Concurrent topical antibiotics: use only under medical guidance. - Severe irritation: discontinue and seek medical advice. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Metronidazole gel can interact with other topical agents and systemic medications.

Major Interactions (Avoid): - Systemic metronidazole therapy: avoid simultaneous use to prevent cumulative exposure. - Known hypersensitivity to nitroimidazoles: contraindicated.

Moderate Interactions (Monitor Closely): - Topical retinoids or exfoliants: may increase local irritation. - Other topical antibiotics (e.g., clindamycin): monitor for additive skin reactions. - Alcohol‑based skin products: may enhance burning sensation. - UV exposure: increased photosensitivity risk, advise sun protection.