Metrocreme

Metronidazole, the active ingredient in Metrocreme, is a Nitroimidazole presented as a topical formulation for skin use. It is indicated for conditions such as rosacea, acne vulgaris, and other skin infections, and is applied directly to the affected area under medical supervision, providing antimicrobial and anti‑inflammatory effects for adult patients.

GNH USA supplies Metrocreme as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality manufacturing standards, regulatory adherence, and reliable global logistics for healthcare providers.

Metronidazole is used topically to treat bacterial and inflammatory skin disorders.

- Rosacea: reduces erythema and papulopustular lesions. - Acne vulgaris: decreases inflammatory lesions and bacterial load. - Dermatological infections: eradicates susceptible anaerobic bacteria and promotes healing.

Topical metronidazole may cause local and systemic adverse reactions.

Common Side Effects: - Skin irritation: mild burning or stinging at the application site. - Itching: localized pruritus. - Dryness: transient skin dryness. - Redness: mild erythema. - Contact dermatitis: allergic skin reaction. - Peeling: superficial desquamation.

Serious or Rare Side Effects: - Severe allergic reaction: anaphylaxis or angioedema. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Extensive skin ulceration or necrosis. - Systemic neurotoxicity: peripheral neuropathy (rare with significant absorption).

When using Metrocreme, consider the following safety measures.

- Pregnancy: safety not established; consult a healthcare professional before use. - Breastfeeding: unknown risk; weigh benefits against potential infant exposure. - Extensive broken skin: avoid application on large open wounds. - Concomitant topical antibiotics: do not combine without medical advice. - Allergic reactions: monitor for signs of hypersensitivity. - Store at room temperature: keep in the original container, protect from moisture and light.

Metronidazole may interact with other medicines when absorbed systemically.

Major Interactions (Avoid): - Alcohol: may cause a disulfiram‑like reaction. - Warfarin: increased anticoagulant effect, risk of bleeding. - Lithium: heightened risk of lithium toxicity.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may reduce metronidazole efficacy. - Other nitroimidazoles: additive toxicity potential. - Oral metronidazole: increased systemic exposure, monitor for side effects.