GNH USA

Europe — EMA

Metoprolol Hexal Z Hexal

GNH USA supplies Metoprolol Hexal Z Hexal (Metoprolol Tartrate), a beta blocker for hypertension, angina, post‑MI care, heart failure and arrhythmias.

Metoprolol Tartrate

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What is Metoprolol Tartrate?

Metoprolol Tartrate, the active ingredient in Metoprolol Hexal Z Hexal, is a beta blocker presented as an oral tablet for oral use. It is used to manage high blood pressure, angina, post‑myocardial‑infarction care, chronic heart failure and certain cardiac arrhythmias in adult patients. GNH USA supplies Metoprolol Hexal Z Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metoprolol Tartrate used for?

Metoprolol Tartrate is a selective β1‑adrenergic blocker that acts on the cardiovascular system to control pressure and rhythm. - Hypertension: lowers systolic and diastolic blood pressure by reducing heart rate and cardiac output. - Angina pectoris: decreases myocardial oxygen demand, relieving chest pain during exertion. - Post‑myocardial infarction: improves survival by limiting ventricular remodeling and reducing recurrent ischemic events. - Chronic heart failure: enhances left‑ventricular function and reduces hospitalisation risk. - Cardiac arrhythmias: controls ventricular rate in atrial fibrillation and other supraventricular tachyarrhythmias.

What are the side effects of Metoprolol Tartrate?

Metoprolol Tartrate may cause a range of adverse reactions, from mild to serious.

Common Side Effects: - Fatigue or tiredness - Dizziness or light‑headedness - Bradycardia (slow heart rate) - Cold extremities - Gastrointestinal upset (nausea, abdominal discomfort) - Sleep disturbances or vivid dreams

Serious or Rare Side Effects: - Severe bradycardia or sinus arrest - High‑grade atrioventricular block - Symptomatic hypotension - Bronchospasm in patients with reactive airway disease - Allergic reactions (rash, angioedema, anaphylaxis) - Depression or mood changes

What precautions apply to Metoprolol Tartrate?

Before prescribing Metoprolol Tartrate, clinicians should evaluate patient‑specific factors and monitor for adverse events. - Cardiovascular assessment: check baseline heart rate, blood pressure, and conduction abnormalities. - Respiratory caution: avoid in patients with severe asthma or chronic obstructive pulmonary disease. - Diabetes monitoring: be aware that beta‑blockade may mask hypoglycaemia symptoms. - Concomitant medications: review for drugs that also lower heart rate or blood pressure. - Pregnancy and lactation: use only if potential benefit justifies potential risk, as safety data are limited. - Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

What does Metoprolol Tartrate interact with?

Metoprolol Tartrate can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Non‑selective beta‑blockers: additive bradycardia and hypotension. - Calcium‑channel blockers (verapamil, diltiazem): increased risk of AV block and severe bradycardia. - Clonidine: abrupt discontinuation may precipitate rebound hypertension.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may enhance hypotensive effect, requiring dose adjustment. - Diuretics: risk of electrolyte disturbances and excessive blood pressure reduction. - Antidiabetic agents (insulin, sulfonylureas): beta‑blockade can mask hypoglycaemia signs, necessitating closer glucose monitoring.

Frequently asked questions

What conditions is Metoprolol Hexal Z Hexal used for?+
Metoprolol Hexal Z Hexal contains metoprolol tartrate, a selective β1‑blocker indicated for hypertension, angina pectoris, post‑myocardial‑infarction management, chronic heart failure, and certain cardiac arrhythmias such as atrial fibrillation.
How does metoprolol tartrate work in the body?+
Metoprolol tartrate blocks β1‑adrenergic receptors in the heart, reducing the effects of adrenaline and noradrenaline. This lowers heart rate, myocardial contractility, and cardiac output, which together help to decrease blood pressure and myocardial oxygen demand.
What is the usual dose of Metoprolol Hexal Z Hexal?+
The appropriate dose of Metoprolol Hexal Z Hexal is determined by the prescribing clinician based on the patient’s condition, response, and tolerability. Dosage regimens are individualized and should follow the prescriber’s instructions.
Is Metoprolol Hexal Z Hexal safe during pregnancy or breastfeeding?+
Safety data for metoprolol tartrate in pregnancy and lactation are limited. It should only be used when the potential benefit outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.
How do I order Metoprolol Hexal Z Hexal from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metoprolol compare with other beta blockers?+
Metoprolol is a cardio‑selective (β1‑selective) blocker, offering a lower risk of bronchospasm compared with non‑selective agents such as propranolol. Its profile makes it a common choice for patients with respiratory concerns, while still providing effective blood‑pressure and anti‑anginal control.
What are the storage requirements for Metoprolol Hexal Z Hexal?+
Metoprolol Hexal Z Hexal tablets should be stored at ambient temperature, below 25 °C, in the original packaging. Protect the product from moisture, heat and direct sunlight to maintain stability.
How is Metoprolol Hexal Z Hexal administered?+
The medication is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.
What are the most serious risks associated with Metoprolol Hexal Z Hexal?+
Serious adverse events can include severe bradycardia, high‑grade atrioventricular block, symptomatic hypotension, bronchospasm in susceptible individuals, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience these symptoms.
Who should not use Metoprolol Hexal Z Hexal?+
Metoprolol should be avoided in patients with known hypersensitivity to metoprolol or other beta‑blockers, those with severe bradycardia, second‑ or third‑degree AV block without a pacemaker, uncompensated heart failure, or severe asthma/COPD where β2‑receptor blockade could worsen airway obstruction.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metoprolol Tartrate
Route
Oral Use
Manufacturer
Hexal Ag
Origin
EU

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