GNH USA

Europe — EMA

Metformine Arrow Lab

GNH USA supplies Metformine Arrow Lab (Metformin), a biguanide oral antidiabetic for type 2 diabetes and PCOS. Request a quote for supply to hospitals.

Metformin Hydrochloride

Request sourcing

1
Pack/s

What is Metformin Hydrochloride?

Metformin, the active ingredient in Metformine Arrow Lab, is a biguanide presented as an oral tablet for oral use. It is used to improve blood glucose control in adults with type 2 diabetes and may be prescribed off‑label for conditions such as polycystic ovary syndrome. GNH USA supplies Metformine Arrow Lab as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metformin Hydrochloride used for?

Metformine Arrow Lab is a biguanide oral antidiabetic that acts on glucose metabolism. - Type 2 diabetes mellitus: lowers fasting and post‑prandial blood glucose levels. - Polycystic ovary syndrome (off‑label): reduces insulin resistance and may improve menstrual regularity. - Prediabetes (off‑label): helps delay progression to overt diabetes when combined with lifestyle changes.

What are the side effects of Metformin Hydrochloride?

Metformine Arrow Lab may cause a range of adverse reactions.

Common Side Effects: - Gastrointestinal upset: nausea, abdominal discomfort, or loss of appetite. - Diarrhea: loose stools, often transient. - Metallic taste: altered taste perception. - Flatulence: increased gas production. - Weight loss: mild reduction in body weight.

Serious or Rare Side Effects: - Lactic acidosis: a rare but life‑threatening metabolic complication. - Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatotoxicity: liver enzyme elevations or injury. - Vitamin B12 deficiency: may develop with long‑term therapy. - Hypoglycaemia: when combined with other glucose‑lowering agents.

What precautions apply to Metformin Hydrochloride?

Metformine Arrow Lab requires careful patient assessment and monitoring. - Renal function: evaluate eGFR before initiation and periodically thereafter. - Hepatic impairment: use with caution in patients with liver disease. - Lactic acidosis risk: avoid in patients with hypoxia, severe infection, or acute heart failure. - Pregnancy: safety category unknown; discuss risks and benefits with a healthcare professional. - Elderly patients: monitor for dehydration and renal function decline. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

What does Metformin Hydrochloride interact with?

Metformine Arrow Lab can interact with several medicines, influencing its efficacy or safety.

Major Interactions (Avoid): - Iodinated contrast agents: increase risk of renal impairment and lactic acidosis. - Cimetidine: may raise metformin plasma concentrations. - Chronic alcohol abuse: elevates the chance of lactic acidosis.

Moderate Interactions (Monitor Closely): - Beta‑blockers: can mask symptoms of hypoglycaemia. - Diuretics: may affect renal clearance of metformin, requiring dose adjustment.

Frequently asked questions

What is Metformine Arrow Lab used for?+
Metformine Arrow Lab contains metformin, a biguanide oral antidiabetic. It is prescribed to improve glycaemic control in adults with type 2 diabetes mellitus and is also used off‑label for conditions such as polycystic ovary syndrome, where it helps reduce insulin resistance.
How does metformin work?+
Metformin lowers blood glucose primarily by activating AMP‑activated protein kinase, which suppresses hepatic glucose production. It also enhances peripheral insulin sensitivity, increasing glucose uptake in muscle and fat, and modestly reduces intestinal glucose absorption, all without stimulating insulin secretion.
What is the usual dose of Metformine Arrow Lab?+
The exact dose of Metformine Arrow Lab is determined by the prescribing clinician based on the individual’s medical condition, renal function, and response to therapy. Dosage adjustments are made according to clinical guidelines and patient tolerance.
Is Metformine Arrow Lab safe in pregnancy or breastfeeding?+
The pregnancy safety category for metformin is listed as unknown. Healthcare providers should evaluate the potential benefits and risks before prescribing it to pregnant or breastfeeding women, and decisions should be made on a case‑by‑case basis.
How do I order Metformine Arrow Lab from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metformine Arrow Lab compare with other antidiabetic classes?+
Compared with sulfonylureas, metformin does not stimulate insulin release, resulting in a lower risk of hypoglycaemia. It also promotes weight stability or modest loss, whereas sulfonylureas may cause weight gain. Metformin is often used as first‑line therapy because of its efficacy, safety profile and cardiovascular benefits.
How should Metformine Arrow Lab be stored and handled?+
Store the product at ambient temperature, below 25 °C, in its original container. Keep it away from moisture and direct sunlight. Do not use if the packaging is damaged or if the tablets appear discoloured.
How is Metformine Arrow Lab administered?+
Metformine Arrow Lab is taken orally, usually with meals to minimise gastrointestinal upset. Patients should swallow the tablet whole with a full glass of water and follow the dosing schedule prescribed by their healthcare professional.
What are the most serious risks associated with Metformine Arrow Lab?+
The most critical risk is lactic acidosis, a rare but potentially fatal condition that can occur in patients with severe renal impairment, hepatic disease, or acute hypoxia. Other serious concerns include severe skin reactions such as Stevens‑Johnson syndrome and significant vitamin B12 deficiency with long‑term use.
Who should not use Metformine Arrow Lab?+
Metformine Arrow Lab is contraindicated in patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²), known hypersensitivity to metformin, acute or chronic metabolic acidosis, and those with conditions predisposing to hypoxia. Clinicians should also avoid use in patients with severe liver disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metformin Hydrochloride
Route
Oral Use
Manufacturer
Arrow Generiques
Origin
EU

Related products