Metformina Teva

Metformin Hydrochloride, the active ingredient in Metformina Teva, is a biguanide presented as an oral tablet for oral administration. It works to lower elevated blood glucose levels and is indicated for the long‑term management of type 2 diabetes mellitus in adult patients.

GNH USA supplies Metformina Teva as a licensed, Good Distribution Practice‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics across global markets with consistent quality and regulatory assurance. The company ensures timely delivery and compliance with local import requirements.

Metformina Teva (metformin hydrochloride) is used in the management of disorders related to glucose metabolism, primarily type 2 diabetes mellitus.

- Type 2 diabetes mellitus: improves glycemic control and reduces HbA1c levels. - Prediabetes (impaired fasting glucose): delays progression to type 2 diabetes. - Polycystic ovary syndrome: helps restore ovulatory cycles and reduce insulin resistance.

Metformina Teva may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, especially during treatment initiation. - Abdominal discomfort: cramping or bloating. - Metallic taste: transient alteration in taste perception. - Weight loss: modest reduction in body weight. - Vitamin B12 deficiency: reduced absorption with long‑term use.

Serious or Rare Side Effects: - Lactic acidosis: life‑threatening accumulation of lactate, especially in renal impairment. - Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Pancreatitis: inflammation of the pancreas. - Hypoglycemia: when combined with other glucose‑lowering agents. - Metabolic acidosis: rare but serious acid‑base disturbance.

Before initiating Metformina Teva, several safety considerations should be reviewed.

- Renal function assessment: evaluate eGFR and avoid use in severe renal impairment. - Lactic acidosis risk: contraindicated in patients with significant hepatic disease or conditions predisposing to hypoxia. - Alcohol consumption: limit intake as it may increase the risk of lactic acidosis. - Surgery or radiologic contrast procedures: withhold metformin before and after the procedure until renal function is confirmed. - Pregnancy and lactation: discuss potential risks and benefits with a healthcare professional. - Store at ambient temperature: keep in the original container, protect from moisture and heat.

Metformina Teva can interact with several medicines, affecting its efficacy or safety.

Major Interactions (Avoid): - Iodinated contrast agents: may cause acute kidney injury; discontinue metformin before and for 48 hours after exposure. - Cimetidine: can increase metformin plasma concentrations, raising the risk of adverse effects.

Moderate Interactions (Monitor Closely): - Beta‑blockers, diuretics, ACE inhibitors: may impair renal function, necessitating renal monitoring. - Alcohol: potentiates the risk of lactic acidosis. - Other antidiabetic agents (e.g., sulfonylureas, insulin): increase the likelihood of hypoglycemia. - Corticosteroids: may elevate blood glucose, requiring dose adjustments.