Metformina Teva

Metformin Hydrochloride, the active ingredient in Metformina Teva, is a biguanide presented as an oral tablet for oral use. It treats type 2 diabetes mellitus by improving blood glucose control in adult patients and belongs to the antidiabetic (oral hypoglycemic) therapeutic class. It is indicated for patients requiring long‑term glycaemic management.

GNH USA supplies Metformina Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metformina Teva (metformin) is used in the management of disorders related to impaired glucose metabolism.

- Type 2 diabetes mellitus: improves glycaemic control and reduces HbA1c levels. - Prediabetes: helps delay progression to overt diabetes by enhancing insulin sensitivity. - Metabolic syndrome: contributes to weight management and improves lipid profile as part of comprehensive therapy.

Metformina Teva may cause a range of adverse reactions, most of which are related to the gastrointestinal system or metabolic disturbances.

Common Side Effects: - Nausea: mild to moderate feeling of sickness. - Diarrhoea: loose stools, often transient. - Abdominal discomfort: cramping or bloating. - Metallic taste: altered taste perception. - Loss of appetite: reduced desire to eat.

Serious or Rare Side Effects: - Lactic acidosis: rare but life‑threatening metabolic acidosis. - Severe hypoglycaemia: especially when combined with insulin or sulfonylureas. - Vitamin B12 deficiency: may develop with long‑term use. - Hepatic dysfunction: abnormal liver enzymes. - Skin rash or hypersensitivity reactions. - Allergic reactions: including angio‑edema.

Before initiating Metformina Teva, several safety considerations should be reviewed.

- Renal function assessment: evaluate eGFR and avoid use if eGFR <30 mL/min/1.73 m². - Hepatic function monitoring: use with caution in patients with liver disease. - Blood glucose monitoring: adjust dose based on fasting and post‑prandial glucose levels. - Concomitant alcohol intake: limit alcohol to reduce risk of lactic acidosis. - Elderly patients: start at lower dose and titrate slowly. - Store at ambient temperature: keep in original container, protect from moisture and heat.

Metformina Teva can interact with several medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Iodinated contrast agents: may precipitate acute renal failure and increase lactic acidosis risk. - Cimetidine: can raise plasma metformin concentrations. - Alcohol excess: synergistic effect on lactate production leading to lactic acidosis.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask hypoglycaemia symptoms. - ACE inhibitors or ARBs: monitor renal function and potassium levels. - Thiazide diuretics: may attenuate glucose‑lowering effect, requiring dose adjustment.