GNH USA

Europe — EMA

Metformin Xr Teva

GNH USA supplies Metformin XR Teva (Metformin Hydrochloride), a biguanide for type 2 diabetes mellitus. Request a quote for global supply.

Metformin Hydrochloride

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What is Metformin Hydrochloride?

Metformin Hydrochloride, the active ingredient in Metformin XR Teva, is a biguanide presented as an extended‑release tablet for oral use. It is employed to lower elevated blood glucose levels in adults with type 2 diabetes mellitus.

GNH USA supplies Metformin XR Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Our distribution network ensures timely delivery and reliable product integrity across diverse markets.

What is Metformin Hydrochloride used for?

Metformin XR Teva is a biguanide indicated for the management of type 2 diabetes mellitus, a chronic disorder of glucose metabolism.

- Type 2 diabetes mellitus: improves glycemic control by lowering fasting and post‑prandial blood glucose levels.

What are the side effects of Metformin Hydrochloride?

Metformin XR Teva may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, often early in therapy. - Abdominal discomfort: cramping or bloating. - Metallic taste: transient alteration of taste perception. - Loss of appetite: reduced desire to eat. - Flatulence: increased intestinal gas.

Serious or Rare Side Effects: - Lactic acidosis: rare but life‑threatening metabolic disturbance. - Severe skin reactions: such as Stevens‑Johnson syndrome. - Hepatic failure: marked liver dysfunction. - Hypoglycemia: uncommon when used alone. - Vitamin B12 deficiency: may develop with long‑term use. - Pancreatitis: rare inflammation of the pancreas.

What precautions apply to Metformin Hydrochloride?

Metformin XR Teva requires careful consideration of patient‑specific factors and clinical monitoring.

- Renal function: avoid or adjust dose in patients with impaired renal clearance. - Hepatic impairment: use with caution in liver disease. - Lactic acidosis risk: discontinue if signs of metabolic acidosis appear. - Alcohol consumption: limit intake to reduce acidosis risk. - Contrast imaging: suspend therapy before iodinated contrast procedures. - Pregnancy category B: use only if clearly needed. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

What does Metformin Hydrochloride interact with?

Metformin XR Teva can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Iodinated contrast agents: may precipitate acute renal failure and lactic acidosis. - Cimetidine: can increase metformin plasma concentrations. - Alcohol: potentiates risk of lactic acidosis.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask hypoglycemia symptoms. - Diuretics: can affect renal function and metformin clearance. - ACE inhibitors/ARBs: monitor renal function and electrolytes. - Other antidiabetic agents: adjust dosing to avoid hypoglycemia. - Thyroid hormones: may require glucose monitoring.

Frequently asked questions

What is Metformin XR Teva used for?+
Metformin XR Teva is an extended‑release formulation of metformin hydrochloride indicated for the treatment of type 2 diabetes mellitus in adults. It helps lower elevated blood glucose levels by improving the body’s response to insulin and reducing glucose production in the liver.
How does Metformin Hydrochloride work?+
Metformin Hydrochloride reduces hepatic glucose output, decreases intestinal absorption of glucose, and enhances peripheral insulin sensitivity. These actions collectively lower fasting and post‑prandial blood glucose without stimulating insulin secretion, making it effective for managing type 2 diabetes.
What is the usual dose of Metformin XR Teva?+
The dosage of Metformin XR Teva is individualized by the prescribing healthcare professional based on the patient’s clinical condition, renal function, and response to therapy. The prescriber determines the appropriate strength and dosing schedule.
Is Metformin XR Teva safe during pregnancy or breastfeeding?+
Metformin XR Teva is classified as pregnancy category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during pregnancy only if the potential benefit justifies the potential risk. Breastfeeding mothers should consult their physician, as metformin is excreted in milk.
How do I order Metformin XR Teva from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA supplies hospitals, pharmacies, and procurement teams worldwide. After verification of trade or institutional credentials, the sales team will provide pricing, availability, shipping details, and any necessary import documentation.
How does Metformin XR compare with immediate‑release metformin?+
Metformin XR provides a once‑daily extended‑release delivery, which can improve gastrointestinal tolerability and adherence compared with immediate‑release formulations that are typically taken two to three times daily. Both contain the same active ingredient and have comparable efficacy when dosed appropriately.
What are the storage requirements for Metformin XR Teva?+
Store Metformin XR Teva at ambient temperature below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed to maintain product stability.
How is Metformin XR Teva administered?+
Metformin XR Teva is taken orally, usually once daily with the evening meal. Tablets should be swallowed whole with a full glass of water; they must not be split, chewed, or crushed, as this can disrupt the extended‑release mechanism.
What are the most serious risks associated with Metformin XR Teva?+
The most serious risk is lactic acidosis, a rare but potentially fatal condition characterized by rapid breathing, muscle pain, and abdominal discomfort. Prompt medical attention is required if these symptoms occur. Other serious concerns include severe skin reactions and hepatic dysfunction.
Who should not use Metformin XR Teva?+
Metformin XR Teva is contraindicated in patients with severe renal impairment (eGFR < 30 mL/min/1.73 m²), known hypersensitivity to metformin, acute or chronic metabolic acidosis, and those who have experienced lactic acidosis while on metformin. Caution is also advised for individuals with hepatic disease or significant alcohol use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metformin Hydrochloride
Route
Oral Use
Manufacturer
Teva B.V
Origin
EU

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