Metformin Teva

Metformin Hydrochloride, the active ingredient in Metformin Teva, is a biguanide presented as a tablet for oral use. It treats type 2 diabetes mellitus in adults by improving blood‑glucose control.

GNH USA supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metformin Teva is an oral biguanide used to manage hyperglycaemia in the type 2 diabetes pathway. - Type 2 diabetes mellitus: lowers fasting and post‑prandial glucose and reduces HbA1c. - Newly diagnosed patients: can be used as first‑line monotherapy to achieve glycaemic targets. - Combination therapy: added to other antidiabetic agents (e.g., sulfonylureas, insulin) to enhance overall glucose control.

Metformin Teva may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhoea: loose stools, often early in therapy. - Metallic taste: transient alteration of taste perception. - Abdominal discomfort: cramping or bloating. - Loss of appetite: reduced desire to eat. - Vitamin B12 deficiency: may develop with long‑term use.

Serious or Rare Side Effects: - Lactic acidosis: rare but life‑threatening metabolic acidosis. - Severe skin reactions: such as Stevens‑Johnson syndrome. - Hepatic dysfunction: elevated liver enzymes. - Hypoglycaemia: when combined with insulin or sulfonylureas. - Acute pancreatitis: very uncommon. - Anemia: due to B12 deficiency.

Metformin Teva requires careful assessment before initiation and during therapy. - Renal function: avoid or adjust dose in patients with impaired creatinine clearance. - Hepatic disease: use with caution; monitor liver enzymes. - Lactic acidosis risk: discontinue before radiologic contrast studies. - Pregnancy and lactation: evaluate risk‑benefit; generally avoided unless clearly needed. - Vitamin B12 monitoring: consider periodic testing during long‑term therapy. - Store at ambient temperature: keep below 25°C in the original container, protect from moisture and light.

Metformin Teva can interact with several medicines, altering its efficacy or safety.

Major Interactions (Avoid): - Iodinated contrast agents: increase risk of lactic acidosis; hold metformin before and after exposure. - Insulin or sulfonylureas: potentiate hypoglycaemia. - Cimetidine: raises metformin plasma concentrations. - Alcohol: may precipitate lactic acidosis. - Renal‑impairing drugs (e.g., NSAIDs): exacerbate accumulation.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask hypoglycaemia symptoms. - Diuretics: affect renal clearance of metformin. - ACE inhibitors/ARBs: monitor renal function and electrolytes. - Thyroid hormones: may alter glucose metabolism. - Oral contraceptives: slight increase in metformin levels.