Metformin Teva

Metformin Hydrochloride, the active ingredient in Metformin Teva, is a biguanide presented as a tablet for oral use. It lowers blood glucose levels in adults with type 2 diabetes mellitus by decreasing hepatic glucose output and improving peripheral insulin sensitivity, thereby supporting better glycemic control.

GNH USA supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metformin Teva is an oral antidiabetic agent indicated for conditions that affect glucose metabolism.

Type 2 diabetes mellitus: improves glycaemic control and reduces HbA1c levels. Prediabetes (impaired glucose tolerance): helps delay progression to overt diabetes. Polycystic ovary syndrome (off‑label): reduces insulin resistance and may improve menstrual regularity.

Metformin Teva may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhoea: frequent loose stools, especially at treatment initiation. - Abdominal discomfort: cramping or bloating. - Metallic taste: transient alteration in taste perception. - Loss of appetite: reduced desire to eat. - Vitamin B12 deficiency: gradual decrease with long‑term use.

Serious or Rare Side Effects: - Lactic acidosis: rare but life‑threatening metabolic acidosis. - Severe hypoglycaemia: uncommon when used alone. - Hepatic dysfunction: elevated liver enzymes. - Skin rash or hypersensitivity: including Stevens‑Johnson syndrome. - Anemia: due to folate or B12 deficiency. - Acute pancreatitis: very rare inflammatory condition.

Metformin Teva requires careful consideration of several clinical factors before and during therapy.

Renal function: assess eGFR and avoid use if eGFR <30 mL/min/1.73 m². Liver disease: contraindicated in severe hepatic impairment. Cardiac failure: use with caution in unstable heart failure. Alcohol consumption: limit intake to reduce lactic acidosis risk. Vitamin B12 monitoring: periodic assessment recommended for long‑term therapy. Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Metformin Teva can interact with other medicines, affecting safety or effectiveness.

Major Interactions (Avoid): - Iodinated contrast agents: may precipitate acute renal failure. - Cimetidine: can increase metformin plasma concentrations. - Nucleoside reverse transcriptase inhibitors: raise risk of lactic acidosis.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask symptoms of hypoglycaemia. - Diuretics: can affect renal clearance of metformin. - ACE inhibitors/ARBs: monitor renal function and electrolytes. - Alcohol: potentiates lactic acidosis risk. - Calcium channel blockers: may modestly increase metformin levels.