Metformin Teva

Metformin, the active ingredient in Metformin Teva, is a Biguanide presented as a tablet for oral use. It treats type 2 diabetes mellitus in adults by improving blood‑sugar control.

GNH USA supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metformin Teva is an oral biguanide used to manage disorders of glucose metabolism. - Type 2 diabetes mellitus: lowers fasting and post‑prandial blood glucose levels. - Prediabetes: helps delay progression to overt diabetes by improving insulin sensitivity. - Polycystic ovary syndrome: reduces insulin resistance and may improve ovulatory function.

Metformin is associated with a range of adverse reactions, most of which are mild and transient.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools, often early in therapy. - Abdominal discomfort: cramping or bloating. - Metallic taste: transient alteration of taste perception. - Weight loss: modest reduction in body weight. - Vitamin B12 deficiency: possible with long‑term use.

Serious or Rare Side Effects: - Lactic acidosis: a rare but life‑threatening metabolic disturbance. - Severe skin reactions: such as Stevens‑Johnson syndrome. - Hepatic dysfunction: elevated liver enzymes or hepatitis. - Hypoglycemia: usually when combined with other antidiabetics. - Anemia: due to reduced red blood cell production. - Renal impairment: worsening kidney function in susceptible patients.

Metformin requires careful assessment of patient health status before initiation. - Renal function: evaluate creatinine clearance; avoid in severe renal impairment. - Hepatic function: use with caution in patients with liver disease. - Lactic acidosis risk: contraindicated in conditions predisposing to hypoxia (e.g., heart failure, severe infection). - Vitamin B12 monitoring: periodic testing recommended for long‑term therapy. - Pregnancy and lactation: assess risk‑benefit; use only if clearly needed. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Metformin may interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Iodinated contrast agents: can precipitate acute renal failure and lactic acidosis. - Cimetidine: may increase metformin plasma concentrations. - Alcohol: potentiates risk of lactic acidosis. - Acute heart failure: heightened risk of hypoxia‑related complications. - Severe renal impairment: markedly raises metformin exposure.

Moderate Interactions (Monitor Closely): - Other antidiabetic agents (e.g., sulfonylureas, insulin): may increase hypoglycemia risk. - Diuretics: can affect renal clearance of metformin. - ACE inhibitors or ARBs: monitor renal function and electrolytes.