Metformin Teva

Metformin, the active ingredient in Metformin Teva, is a biguanide presented as a tablet for oral use. It is used to improve blood glucose control in adults with type 2 diabetes mellitus. GNH USA supplies Metformin Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Metformin Teva is a biguanide that acts on glucose metabolism to manage several insulin‑related conditions.

Type 2 diabetes mellitus: lowers fasting and post‑prandial blood glucose levels. Prediabetes: helps delay progression to overt diabetes by improving insulin sensitivity. Polycystic ovary syndrome (PCOS): reduces insulin resistance and may improve menstrual regularity.

Metformin may cause a range of adverse reactions, most of which are related to the gastrointestinal tract, while rare events can be serious.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhea: loose stools, often transient. - Abdominal discomfort: cramping or pain. - Metallic taste: transient alteration of taste. - Loss of appetite: reduced desire to eat. - Flatulence: increased gas production.

Serious or Rare Side Effects: - Lactic acidosis: rare but life‑threatening metabolic disturbance. - Severe hypoglycemia: usually when combined with other glucose‑lowering agents. - Hepatic failure: rare liver dysfunction. - Allergic reactions: rash, pruritus, or angioedema. - Vitamin B12 deficiency: long‑term use may reduce absorption. - Skin discoloration: rare hyperpigmentation.

Metformin should be used with careful clinical monitoring and patient education.

Renal function: assess creatinine clearance before initiation and periodically thereafter. Liver disease: avoid in patients with significant hepatic impairment. Contrast imaging: discontinue at least 48 hours before iodinated contrast procedures. Alcohol consumption: limit intake to reduce risk of lactic acidosis. Pregnancy and lactation: evaluate risk‑benefit; use only if clearly needed. Store at ambient temperature (below 25°C): keep in the original container, protect from moisture.

Metformin may interact with several medicines, requiring dose adjustments or monitoring.

Major Interactions (Avoid): - Iodinated contrast agents: increase risk of lactic acidosis. - MAO inhibitors: may potentiate hypotensive effects. - Cimetidine: can raise metformin plasma concentrations.

Moderate Interactions (Monitor Closely): - Alcohol: enhances risk of lactic acidosis. - Diuretics: may affect renal clearance of metformin. - Corticosteroids: can raise blood glucose, requiring dose titration. - Beta‑blockers: may mask hypoglycemia symptoms. - Other antidiabetic agents: increase risk of hypoglycemia.