GNH USA

Europe — EMA

Metaoxedrin Minims Bausch + Lomb Ireland Limited

GNH USA supplies Metaoxedrin Minims (Phenylephrine Hydrochloride), a sympathomimetic ocular decongestant for redness relief and pupil dilation.

Phenylephrine Hydrochloride

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What is Phenylephrine Hydrochloride?

Phenylephrine Hydrochloride, the active ingredient in Metaoxedrin Minims, is a sympathomimetic (alpha‑1 adrenergic agonist) presented as an ophthalmic solution for ocular use. It reduces conjunctival redness and can dilate the pupil to aid eye examinations. It is indicated for the temporary relief of ocular redness associated with minor irritations and is also employed by ophthalmologists to achieve pharmacologic mydriasis during diagnostic procedures.

GNH USA supplies Metaoxedrin Minims as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with established distribution networks across Europe, Asia and the Americas.

What is Phenylephrine Hydrochloride used for?

Phenylephrine Hydrochloride ophthalmic solution acts on the ocular vasculature by stimulating alpha‑1 adrenergic receptors, leading to vasoconstriction that relieves redness and produces pupil dilation, making it useful in several ophthalmic situations.

Ocular redness: reduces conjunctival hyperemia for temporary cosmetic relief. Conjunctival hyperemia: diminishes vessel engorgement to improve visual comfort. Mydriasis for eye examination: dilates the pupil to facilitate diagnostic procedures. Diagnostic pupil dilation: enables thorough retinal examination. Anterior segment imaging: provides adequate pupil size for photographic documentation.

What are the side effects of Phenylephrine Hydrochloride?

Common Side Effects: - Transient burning or stinging sensation in the eye. - Mild ocular irritation or itching. - Temporary blurred vision after administration. - Mild headache.

Serious or Rare Side Effects: - Significant increase in intraocular pressure. - Allergic reactions such as eyelid swelling, rash, or angioedema. - Severe ocular pain or photophobia. - Systemic hypertension or cardiovascular events.

What precautions apply to Phenylephrine Hydrochloride?

Phenylephrine ophthalmic solution should be used with caution in the following situations.

Contraindicated in narrow‑angle glaucoma: risk of further angle closure. Use with caution in cardiovascular disease: may raise blood pressure. Avoid concurrent use with other mydriatic agents: additive effect. Do not use if hypersensitivity to phenylephrine or any excipients: risk of allergic response. Store at room temperature: keep in original container, protect from light and moisture.

What does Phenylephrine Hydrochloride interact with?

Phenylephrine ophthalmic solution may interact with other systemic or ocular agents.

Major Interactions (Avoid): - MAO inhibitors: may precipitate hypertensive crisis. - Systemic sympathomimetics (e.g., pseudoephedrine): additive vasoconstriction. - Tricyclic antidepressants: increased cardiovascular stimulation.

Moderate Interactions (Monitor Closely): - Beta‑blockers: may mask tachycardia. - Antihypertensive therapy: phenylephrine may reduce efficacy. - Other ocular vasoconstrictors: additive ocular effects.

Frequently asked questions

What is Metaoxedrin Minims used for?+
Metaoxedrin Minims is an ophthalmic solution containing phenylephrine hydrochloride. It is used to temporarily relieve ocular redness caused by minor irritations and to produce pharmacologic pupil dilation (mydriasis) during eye examinations or diagnostic procedures.
How does phenylephrine hydrochloride work in the eye?+
Phenylephrine hydrochloride selectively stimulates alpha‑1 adrenergic receptors on conjunctival blood vessels and the iris dilator muscle. This causes vasoconstriction, reducing redness, and contracts the dilator muscle, leading to pupil enlargement, which facilitates ocular assessment.
What is the usual dose of Metaoxedrin Minims?+
The dosing regimen for Metaoxedrin Minims is determined by the prescribing clinician. Typically, a single drop is instilled in the affected eye(s) as directed, and the frequency is adjusted based on the specific indication and patient response.
Is Metaoxedrin Minims safe during pregnancy or breastfeeding?+
Safety data for phenylephrine ophthalmic use in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a healthcare professional.
How do I order Metaoxedrin Minims from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metaoxedrin Minims compare with other ocular decongestants?+
Metaoxedrin Minims (phenylephrine) provides both vasoconstriction and mydriasis, whereas many alternatives such as naphazoline primarily offer vasoconstriction without pupil dilation. Phenylephrine’s dual action makes it useful when both redness relief and pupil enlargement are desired.
What are the storage and handling requirements for Metaoxedrin Minims?+
Store the ophthalmic solution at room temperature, preferably below 25 °C. Keep the bottle tightly closed, protect it from direct light, and retain it in the original packaging to avoid moisture exposure. Do not freeze the product.
How is Metaoxedrin Minims administered?+
Metaoxedrin Minims is applied topically to the eye. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place a single drop into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption.
What are the most serious risks associated with Metaoxedrin Minims?+
Serious risks include a marked increase in intraocular pressure, especially in patients with narrow‑angle glaucoma, and systemic hypertension or cardiovascular events due to systemic absorption. Allergic reactions such as eyelid swelling or rash also require immediate medical attention.
Who should not use Metaoxedrin Minims?+
Individuals with a known hypersensitivity to phenylephrine or any formulation excipients should avoid the product. It is also contraindicated in patients with narrow‑angle or acute angle‑closure glaucoma, and should be used with caution in those with uncontrolled cardiovascular disease.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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