GNH USA

Europe — EMA

Metamizol Teva-Ratiopharm (Metamizole Magnesium)

GNH USA supplies Metamizol Teva-Ratiopharm (Metamizole), a pyrazolone analgesic for pain and fever. Request a quote for global supply, available worldwide.

Metamizole Magnesium

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What is Metamizole Magnesium?

Metamizole, the active ingredient in Metamizol Teva-Ratiopharm, is a pyrazolone analgesic presented as an oral formulation for systemic use. It provides analgesic and antipyretic effects for the treatment of pain and fever in adults.

GNH USA supplies Metamizol Teva-Ratiopharm as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Magnesium used for?

Metamizol Teva-Ratiopharm acts as an analgesic and antipyretic within the pyrazolone drug class.

- Pain: reduces moderate to severe acute and chronic pain. - Fever: lowers elevated body temperature associated with infection or inflammation. - Visceral pain: alleviates pain originating from internal organs. - Postoperative pain: manages pain following surgical procedures.

What are the side effects of Metamizole Magnesium?

Metamizole may cause a range of adverse reactions.

Common Side Effects: - Nausea - Dizziness - Hypotension - Rash or mild skin irritation - Headache - Vomiting

Serious or Rare Side Effects: - Agranulocytosis (severe reduction in white blood cells) - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Anaphylactic shock - Severe liver injury - Acute kidney failure - Other serious blood dyscrasias

What precautions apply to Metamizole Magnesium?

Before prescribing Metamizol Teva-Ratiopharm, clinicians should consider several safety measures.

- Assess renal function: adjust use in severe renal impairment. - Monitor blood counts: risk of agranulocytosis requires periodic hematologic testing. - Avoid in known hypersensitivity: discontinue immediately if allergic reaction occurs. - Use caution in hepatic disease: monitor liver enzymes during therapy. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

What does Metamizole Magnesium interact with?

Metamizol Teva-Ratiopharm can interact with other medicines; awareness of interaction severity is essential.

Major Interactions (Avoid): - Concurrent use with other myelosuppressive agents: increased risk of bone marrow suppression. - Combination with other NSAIDs or COX inhibitors: heightened gastrointestinal toxicity. - Co-administration with anticoagulants: potential for enhanced bleeding.

Moderate Interactions (Monitor Closely): - Interaction with ACE inhibitors: may potentiate hypotensive effect. - Use with diuretics: monitor electrolytes and renal function. - Concurrent use with carbamazepine: may reduce analgesic efficacy.

Frequently asked questions

What is Metamizol Teva-Ratiopharm used for?+
Metamizol Teva-Ratiopharm is a prescription‑only analgesic and antipyretic containing Metamizole. It is indicated for the management of moderate to severe pain, fever, visceral pain, and postoperative pain in adult patients when other treatments are insufficient or unsuitable.
How does Metamizole work?+
Metamizole works by inhibiting cyclooxygenase enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish peripheral pain signaling and the central fever response, resulting in analgesic and antipyretic effects.
What is the usual dose of Metamizol Teva-Ratiopharm?+
The appropriate dose of Metamizol Teva-Ratiopharm is determined by the prescribing clinician based on the patient’s specific condition, severity of pain, and individual health factors. Dosage regimens are individualized and should follow the prescriber’s instructions.
Is Metamizol safe in pregnancy or breastfeeding?+
Safety data for Metamizole during pregnancy and lactation are limited. It should only be used if the potential therapeutic benefit justifies any potential risk to the fetus or infant, and only after consultation with a qualified healthcare professional.
How do I order Metamizol Teva-Ratiopharm from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity and providing institutional or trade credentials. GNH USA will respond with pricing, availability, shipping details (including any cold‑chain requirements if applicable), and the necessary import documentation.
How does Metamizol compare with other analgesics?+
Compared with traditional NSAIDs, Metamizole provides analgesic and antipyretic effects via a distinct mechanism and may have a lower risk of gastrointestinal irritation. However, it carries a rare but serious risk of agranulocytosis. Choice of therapy should be based on individual patient risk factors and clinical judgment.
What are the storage requirements for Metamizol Teva-Ratiopharm?+
Store the product at ambient temperature below 25 °C. Keep it in the original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.
How is Metamizol Teva-Ratiopharm administered?+
Metamizol Teva-Ratiopharm is taken orally as directed by a healthcare professional, typically with a glass of water. Tablets or oral solutions should be swallowed whole unless the prescriber provides specific instructions for splitting or crushing.
What are the most serious risks to watch for with Metamizol?+
The most serious adverse reactions include agranulocytosis (a severe drop in white blood cells), life‑threatening skin reactions such as Stevens‑Johnson syndrome, and anaphylactic shock. Patients should be monitored for signs of infection, skin changes, or allergic reactions, and treatment should be stopped immediately if these occur.
Who should not use Metamizol Teva-Ratiopharm?+
Metamizol should be avoided in individuals with known hypersensitivity to Metamizole or other pyrazolones, patients with a history of agranulocytosis, and those with severe hepatic or renal impairment unless a physician determines that the benefits outweigh the risks.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metamizole Magnesium
Route
Oral Use
Manufacturer
Teva Pharma S.L.U.,
Origin
EU

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