GNH USA

Europe — EMA

Metamizol Tarbis

GNH USA supplies Metamizol Tarbis (Metamizole), a pyrazolone analgesic for acute pain, post‑operative pain and fever. Request a quote for global supply.

Metamizole Magnesium

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Pack/s

What is Metamizole Magnesium?

Metamizole, the active ingredient in Metamizol Tarbis, is a pyrazolone analgesic presented as an oral formulation for oral use. It treats acute and post‑operative pain, fever, and visceral colic in adult patients.

GNH USA supplies Metamizol Tarbis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Magnesium used for?

Metamizole is used to manage pain and fever by inhibiting prostaglandin synthesis.

- Acute pain: provides rapid relief of moderate to severe pain. - Post‑operative pain: reduces pain intensity after surgical procedures. - Fever: lowers elevated body temperature in febrile states. - Colic and visceral pain: alleviates spasm‑related abdominal discomfort.

What are the side effects of Metamizole Magnesium?

Metamizole may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea - Vomiting - Dizziness - Headache - Skin rash - Mild hypotension

Serious or Rare Side Effects: - Agranulocytosis (dangerous drop in white blood cells) - Anaphylactic reactions - Stevens‑Johnson syndrome - Severe blood dyscrasias - Hepatotoxicity - Acute kidney injury

What precautions apply to Metamizole Magnesium?

Use Metamizole with caution and observe the following precautions.

- Renal impairment: assess kidney function before initiating therapy. - Hepatic disease: monitor liver enzymes during treatment. - History of blood disorders: avoid or closely monitor blood counts. - Concomitant NSAIDs: increased risk of gastrointestinal bleeding. - Pregnancy: safety unknown; avoid unless clearly needed. - Store at below 25°C: keep in the original pack, protect from moisture.

What does Metamizole Magnesium interact with?

Metamizole can interact with other medicines; consider the interactions below.

Major Interactions (Avoid): - Cytotoxic chemotherapy agents: heightened bone‑marrow suppression risk. - Anticoagulants (e.g., warfarin): may increase bleeding tendency. - Sulfonamide antibiotics: potential cross‑reactivity.

Moderate Interactions (Monitor Closely): - ACE inhibitors: may enhance hypotensive effects. - Diuretics: possible alteration of renal function. - Lithium: risk of elevated lithium concentrations.

Frequently asked questions

What is Metamizol Tarbis used for?+
Metamizol Tarbis contains the pyrazolone analgesic metamizole and is indicated for the relief of moderate to severe acute pain, post‑operative pain, high fever, and visceral or colicky pain. It is prescribed for adult patients when rapid analgesic and antipyretic effects are required.
How does Metamizole work?+
Metamizole inhibits cyclooxygenase enzymes, which reduces the production of prostaglandins that mediate pain and fever. In addition, it influences central pain pathways in the spinal cord, providing a combined peripheral and central analgesic effect that also lowers body temperature.
What is the usual dose of Metamizol Tarbis?+
The specific dose of Metamizol Tarbis is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, and individual health factors. Healthcare professionals follow local prescribing guidelines and adjust the regimen as needed for safety and efficacy.
Is Metamizol Tarbis safe during pregnancy or breastfeeding?+
Safety data for metamizole in pregnancy and lactation are limited, and the pregnancy category is listed as unknown. Therefore, it should only be used when the potential benefit justifies the potential risk to the fetus or infant, and only under medical supervision.
How do I order Metamizol Tarbis from GNH USA?+
To request Metamizol Tarbis, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does Metamizol compare with other analgesics?+
Metamizole offers rapid analgesic and antipyretic effects similar to non‑steroidal anti‑inflammatory drugs (NSAIDs) but with a different chemical class. Unlike opioids, it does not act on opioid receptors, reducing the risk of dependence, but it carries a rare risk of severe blood disorders that are not typical of standard NSAIDs.
How should Metamizol Tarbis be stored and handled?+
Metamizol Tarbis should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and potency throughout its shelf life.
How is Metamizol Tarbis administered?+
Metamizol Tarbis is administered orally. The tablets or oral formulation should be swallowed whole with a full glass of water. It can be taken with or without food, but patients should follow the prescribing clinician’s instructions regarding timing and any accompanying fluids.
What are the most serious risks to watch for when using Metamizol Tarbis?+
The most serious adverse reactions include agranulocytosis, a potentially life‑threatening drop in white blood cells, and severe allergic responses such as anaphylaxis or Stevens‑Johnson syndrome. Patients should be advised to seek immediate medical attention if they develop signs of infection, rash, or breathing difficulties.
Who should not use Metamizol Tarbis?+
Metamizol Tarbis should be avoided in individuals with known hypersensitivity to metamizole or other pyrazolones, those with a history of severe blood dyscrasias, and patients with significant renal or hepatic impairment unless closely monitored. Pregnant or breastfeeding women should only use it when clearly indicated by a healthcare professional.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Metamizole Magnesium
Route
Oral Use
Manufacturer
Tarbis Farma, S.L.
Origin
EU

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