GNH USA

Europe — EMA

Metamizol Tad (Metamizole Sodium Monohydrate)

GNH USA supplies Metamizol Tad (Metamizole), a pyrazolone analgesic and antipyretic for pain and fever. Request a quote for global supply to hospitals.

Metamizole Sodium Monohydrate

Request sourcing

1
Pack/s

What is Metamizole Sodium Monohydrate?

Metamizole Sodium Monohydrate, the active ingredient in Metamizol Tad, is a pyrazolone presented as a parenteral solution for intramuscular and intravenous use. It provides analgesic and antipyretic effects for adults experiencing pain or fever, including postoperative discomfort and visceral colic.

GNH USA supplies Metamizol Tad as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company follows EU‑quality standards and offers reliable global distribution.

What is Metamizole Sodium Monohydrate used for?

Metamizole is employed to manage pain and fever across several clinical settings.

Pain: provides relief of moderate to severe acute pain Fever: reduces elevated body temperature in febrile patients Postoperative pain: controls pain following surgical procedures Colic: alleviates visceral pain associated with intestinal colic

What are the side effects of Metamizole Sodium Monohydrate?

Metamizole may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Hypotension: transient drop in blood pressure after injection - Nausea: mild to moderate feeling of queasiness - Vomiting: occasional emesis following administration - Injection site reactions: pain, redness or swelling at the site

Serious or Rare Side Effects: - Agranulocytosis: severe reduction in white blood cells - Anaphylaxis: life‑threatening allergic reaction - Stevens‑Johnson syndrome: severe skin and mucous membrane disorder - Hepatic dysfunction: abnormal liver enzyme elevations

What precautions apply to Metamizole Sodium Monohydrate?

Before using Metamizol Tad, consider the following precautions.

Assess renal function: adjust use in patients with renal impairment Monitor blood counts: watch for signs of agranulocytosis Use cautiously in hepatic disease: avoid in severe liver dysfunction Avoid in known hypersensitivity: discontinue if allergic reaction occurs Do not combine with other myelosuppressive agents: increased risk of blood disorders Store at ambient temperature: keep in original packaging, protect from moisture and light

What does Metamizole Sodium Monohydrate interact with?

Metamizol Tad can interact with several drug classes; awareness of these interactions helps minimize risk.

Major Interactions (Avoid): - Concurrent myelosuppressive drugs: may amplify risk of agranulocytosis - Other NSAIDs: increase gastrointestinal bleeding potential - Drugs causing agranulocytosis (e.g., carbamazepine): heightened hematologic risk - Anticoagulants: may enhance bleeding tendency

Moderate Interactions (Monitor Closely): - Antihypertensives: additive hypotensive effect - Diuretics: possible electrolyte disturbances - CYP‑metabolized drugs: may alter plasma concentrations of co‑administered agents

Frequently asked questions

What is Metamizol Tad used for?+
Metamizol Tad contains the pyrazolone analgesic Metamizole and is prescribed to relieve moderate to severe pain and to reduce fever. It is commonly used after surgery, for acute visceral pain such as colic, and in other situations where rapid analgesic and antipyretic effects are needed.
How does Metamizole work?+
Metamizole works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production and reduces inflammation‑related pain. It also influences endogenous opioid pathways, enhancing pain‑modulating signals in the central nervous system. Together, these actions provide both analgesic and antipyretic effects.
What is the usual dose of Metamizol Tad?+
The exact dose of Metamizol Tad is determined by the prescribing clinician based on the patient’s condition, age, weight, and response to therapy. Dosing is individualized and administered by a healthcare professional via intramuscular or intravenous injection.
Is Metamizol Tad safe during pregnancy or breastfeeding?+
Safety data for Metamizole in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and only under close medical supervision.
How do I order Metamizol Tad from GNH USA?+
To place an order, submit an enquiry on the Metamizol Tad product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and necessary import documentation.
How does Metamizol compare with other analgesics?+
Metamizole offers rapid analgesic and antipyretic effects similar to non‑steroidal anti‑inflammatory drugs (NSAIDs) but is often chosen when NSAIDs are contraindicated or when a stronger pain relief is required. Unlike opioids, it does not act on µ‑receptors, reducing the risk of typical opioid‑related side effects, though it carries a unique risk of agranulocytosis.
How should Metamizol Tad be stored?+
Store Metamizol Tad at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly sealed when not in use.
How is Metamizol Tad administered?+
Metamizol Tad is supplied as a sterile injectable solution and must be administered by a qualified healthcare professional. It can be given either intramuscularly or intravenously, depending on the clinical situation and the prescriber’s recommendation.
What are the most serious risks to watch for with Metamizol Tad?+
The most serious adverse events include agranulocytosis, which can lead to severe infections, and life‑threatening allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Immediate medical attention is required if patients develop signs of infection, unexplained fever, skin rash, or breathing difficulties.
Who should not use Metamizol Tad?+
Metamizol Tad should be avoided in individuals with known hypersensitivity to Metamizole or other pyrazolones, in patients with severe hepatic impairment, and in those who have previously experienced agranulocytosis. Caution is also advised for patients with uncontrolled hypertension or active bleeding disorders.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Metamizole Sodium Monohydrate
Route
Intramuscular Use , Intravenous Use
Manufacturer
Tad Pharma Gmbh
Origin
EU

Related products

Afexil

Afexil

Metamizole Sodium Monohydrate

Zentiva, K.S.
EU
Afexil

Afexil

Metamizole Sodium Monohydrate

Zentiva, K.S.
EU
Algiotop

Algiotop

Metamizole Sodium Monohydrate

S.C. Santa S.A.
EU
Algocalmin

Algocalmin

Metamizole Sodium Monohydrate

Zentiva S.A.
EU