GNH USA

Europe — EMA

Metamizol Stada

GNH USA supplies Metamizol Stada (Metamizole), a pyrazolone analgesic and antipyretic for pain and fever. Request a quote for global supply.

Metamizole Sodium Monohydrate

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What is Metamizole Sodium Monohydrate?

Metamizole Sodium Monohydrate, the active ingredient in Metamizol Stada, is a pyrazolone presented as an oral dosage form for oral use. It treats pain and fever in adults and children as directed by a healthcare professional.

GNH USA supplies Metamizol Stada as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Sodium Monohydrate used for?

Metamizol Stada is a pyrazolone analgesic and antipyretic used to manage pain and fever.

- Acute pain: provides rapid relief of moderate to severe pain. - Post‑operative pain: helps control pain after surgical procedures. - Fever: reduces elevated body temperature associated with infectious or inflammatory conditions.

What are the side effects of Metamizole Sodium Monohydrate?

Metamizol Stada may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Nausea or vomiting - Dizziness or light‑headedness - Mild skin rash or itching - Hypotension, especially with rapid intravenous administration - Transient liver enzyme elevation

Serious or Rare Side Effects: - Agranulocytosis or severe neutropenia - Aplastic anemia or other bone‑marrow suppression - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Anaphylactic or severe allergic reactions - Hepatic failure or severe hepatitis

What precautions apply to Metamizole Sodium Monohydrate?

Before initiating therapy with Metamizol Stada, consider the following precautions. - Blood count monitoring: perform baseline and periodic complete blood counts to detect early signs of agranulocytosis. - Renal or hepatic impairment: use with caution and adjust dosing as clinically indicated. - Known hypersensitivity: avoid in patients with documented allergy to metamizole or other pyrazolones. - Concomitant myelosuppressive drugs: monitor closely for additive bone‑marrow toxicity. - Medical supervision: only use under prescription and regular clinical review. - Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

What does Metamizole Sodium Monohydrate interact with?

Metamizol Stada can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of bleeding. - Other myelosuppressive agents: heightened risk of severe blood dyscrasias. - ACE inhibitors or diuretics: may potentiate hypotensive effects.

Moderate Interactions (Monitor Closely): - Sulfonamide antibiotics: potential additive hypersensitivity. - Lithium: possible increase in lithium serum levels. - Antiepileptic drugs: may alter seizure threshold in susceptible individuals.

Frequently asked questions

What is Metamizol Stada used for?+
Metamizol Stada contains metamizole sodium monohydrate, a pyrazolone that is prescribed to relieve moderate to severe pain and to reduce fever. It is commonly used in acute pain settings, postoperative pain management, and for febrile conditions when other antipyretics are unsuitable.
How does metamizole work?+
Metamizole works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production. This action reduces peripheral inflammation and also provides central analgesic effects by modulating spinal pain pathways, resulting in both pain relief and fever reduction.
What is the usual dose of Metamizol Stada?+
The appropriate dose of Metamizol Stada is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and response to therapy. Dosing instructions are provided on the prescription label and should be followed exactly as directed.
Is Metamizol Stada safe during pregnancy or breastfeeding?+
Safety data for metamizole in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.
How do I order Metamizol Stada from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Metamizol Stada compare with other analgesics?+
Metamizole belongs to the pyrazolone class, offering strong analgesic and antipyretic effects similar to non‑steroidal anti‑inflammatory drugs (NSAIDs) but with a different safety profile. Unlike many NSAIDs, it has a lower risk of gastrointestinal irritation but carries a rare risk of severe blood disorders such as agranulocytosis.
What are the storage requirements for Metamizol Stada?+
Metamizol Stada should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and extreme heat to maintain its stability and potency.
How is Metamizol Stada administered?+
Metamizol Stada is supplied as an oral dosage form and is taken by mouth with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water; it should not be crushed or chewed unless specifically instructed.
What are the most serious risks associated with Metamizol Stada?+
The most serious adverse reactions include agranulocytosis, aplastic anemia, severe skin reactions such as Stevens‑Johnson syndrome, and anaphylaxis. Patients should be monitored for signs of infection, unexplained fever, rash, or breathing difficulties, and seek immediate medical attention if these occur.
Who should not use Metamizol Stada?+
Metamizol Stada should be avoided in individuals with known hypersensitivity to metamizole or other pyrazolones, in patients with a history of severe blood dyscrasias, and in those currently receiving other myelosuppressive therapies unless closely supervised by a physician.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Metamizole Sodium Monohydrate
Route
Oral Use
Manufacturer
Stadapharm Gmbh
Origin
EU

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