GNH USA

Europe — EMA

Metamizol Noridem (Metamizole Sodium Monohydrate)

GNH USA supplies Metamizol Noridem (Metamizole Sodium), a pyrazolone analgesic and antipyretic for pain, fever and postoperative pain. Request a quote.

Metamizole Sodium Monohydrate

Request sourcing

1
Pack/s

What is Metamizole Sodium Monohydrate?

Metamizole sodium, the active ingredient in Metamizol Noridem, is a pyrazolone presented as an injectable solution for intramuscular and intravenous use. It treats pain and fever, including postoperative pain, in adult patients.

GNH USA supplies Metamizol Noridem as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Metamizole Sodium Monohydrate used for?

Metamizole sodium is used for managing pain and fever through its analgesic and antipyretic actions.

Pain: provides relief of moderate to severe acute pain Fever: reduces elevated body temperature in febrile conditions Postoperative pain: controls pain following surgical procedures

What are the side effects of Metamizole Sodium Monohydrate?

Metamizole Noridem may cause adverse reactions that vary in frequency and severity.

Common Side Effects: - Injection site pain - Nausea - Dizziness - Transient hypotension

Serious or Rare Side Effects: - Agranulocytosis - Severe allergic reactions (anaphylaxis) - Stevens‑Johnson syndrome

What precautions apply to Metamizole Sodium Monohydrate?

Prior to initiating therapy, clinicians should consider several safety measures.

Assess blood counts before therapy: monitor for neutropenia Use with caution in renal impairment: adjust monitoring Avoid in known hypersensitivity to pyrazolones: contraindicated Administer only under medical supervision: ensure appropriate indication Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake

What does Metamizole Sodium Monohydrate interact with?

Metamizole Noridem can interact with other medicines, requiring attention to avoid harmful effects.

Major Interactions (Avoid): - Concomitant myelosuppressive agents: increased risk of agranulocytosis - ACE inhibitors: may potentiate hypotension - Other NSAIDs: additive gastrointestinal and renal risk

Moderate Interactions (Monitor Closely): - Anticoagulants: increased bleeding tendency - Diuretics: possible electrolyte disturbances - Other antipyretics: may mask fever response

Frequently asked questions

What is Metamizol Noridem used for?+
Metamizol Noridem is a prescription injectable analgesic and antipyretic containing metamizole sodium. It is used to relieve moderate to severe acute pain, reduce fever, and manage postoperative pain in adult patients, administered by intramuscular or intravenous route under medical supervision.
How does metamizole sodium work?+
Metamizole sodium works by inhibiting cyclooxygenase enzymes, which reduces prostaglandin synthesis, and by modulating other inflammatory mediators. This dual action decreases pain signaling and lowers the hypothalamic set‑point for temperature, providing analgesic and antipyretic effects, although the precise mechanisms are not fully defined.
What is the usual dose of Metamizol Noridem?+
The specific dose and frequency are determined by the prescribing clinician based on the patient’s condition, severity of pain or fever, and the chosen route of administration. Dosing is individualized and should follow the prescriber’s instructions and local regulatory guidelines.
Is Metamizol Noridem safe during pregnancy or breastfeeding?+
Safety data for metamizole sodium in pregnancy and lactation are limited, and the product is classified with an unknown pregnancy category. It should only be used if the potential benefit justifies the potential risk, and a healthcare professional must evaluate each case individually.
How do I order Metamizol Noridem from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and necessary import documentation.
How does Metamizol Noridem compare with other analgesics?+
Compared with traditional NSAIDs, metamizole sodium offers strong analgesic and antipyretic effects with a lower incidence of gastrointestinal irritation, but it carries a risk of rare blood dyscrasias such as agranulocytosis. Unlike opioids, it does not cause respiratory depression, making it a useful alternative for certain acute pain scenarios under supervision.
What are the storage requirements for Metamizol Noridem?+
Metamizol Noridem should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. The product should remain in its original packaging until use to maintain stability and sterility.
How is Metamizol Noridem administered?+
The injectable solution is administered by a qualified healthcare professional either intramuscularly or intravenously, according to the prescriber’s instructions. Proper aseptic technique and any required dilution should be observed to ensure safe delivery.
What are the most serious risks associated with Metamizol Noridem?+
The most serious adverse reactions include agranulocytosis, severe allergic reactions such as anaphylaxis, and rare skin disorders like Stevens‑Johnson syndrome. Patients should be monitored for signs of infection, rash, or breathing difficulty, and immediate medical attention is required if these occur.
Who should not use Metamizol Noridem?+
Metamizol Noridem is contraindicated in individuals with known hypersensitivity to metamizole or other pyrazolones, patients with a history of agranulocytosis, and should be used with caution in those with severe renal or hepatic impairment. It should also be avoided in children unless specifically prescribed by a specialist.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
Send a sourcing enquiry for this product →

Product details

Drug
Metamizole Sodium Monohydrate
Route
Intramuscular Use , Intravenous Use
Manufacturer
Noridem Enterprises Ltd
Origin
EU

Related products

Afexil

Afexil

Metamizole Sodium Monohydrate

Zentiva, K.S.
EU
Afexil

Afexil

Metamizole Sodium Monohydrate

Zentiva, K.S.
EU
Algiotop

Algiotop

Metamizole Sodium Monohydrate

S.C. Santa S.A.
EU
Algocalmin

Algocalmin

Metamizole Sodium Monohydrate

Zentiva S.A.
EU